Engineered Soft Materials and Interfaces

工程软材料和界面

• 批准号: CRC-2016-00017
• 负责人: Ramchandran, Arun
• 金额: $ 8.74万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695434
• 关键词: Engineered; Soft; Materials; Interfaces

Materials containing soft particles are ubiquitous in daily life and in the industry, and constitute a multibillion dollar worldwide market. However, due to the trial-and-error, empirical nature of their development, an understanding of how the constituent components and processing variables may be manipulated to obtain a desired product function and lower environment footprint, is still lacking. This program will systematically develop these relationships. It will also elucidate how blood clots, which are essentially soft gel particles, embolize blood vessels in diseases such as embolic strokes and pulmonary embolism, and will engineer the drug cocktail most efficient at dissolving embolized clots.

含有软颗粒的材料在日常生活和工业中无处不在，并构成了数十亿美元的全球市场。 然而，由于其开发的试错和经验性质，仍然缺乏对如何操纵组成部件和加工变量以获得所需产品功能和较低环境足迹的理解。 该计划将系统地发展这些关系。 它还将阐明血凝块（本质上是软凝胶颗粒）如何在栓塞性中风和肺栓塞等疾病中栓塞血管，并将设计最有效溶解栓塞凝块的药物鸡尾酒。