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Understanding the effects of ERK hyperactivation in cancer: implications for therapy

Understanding the effects of ERK hyperactivation in cancer: implications for therapy
了解 ERK 过度激活对癌症的影响：对治疗的影响
批准号：
445201
负责人：
Lockwood William W
金额：
$69.66万
依托单位：
B.C. Cancer Research Centre (Vancouver)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
未结题
起止时间：
2021-04-01 至 2026-04-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=445201&lang=en
关键词：
Cancer Biology Cancer Signaling Drug Development Erk Kinases Lung Cancer Mouse Models Oncogenes Phosphatases Synthetic Lethality

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英文摘要
Lung cancer is the leading cause of cancer death in Canada and worldwide, suffering from a late stage of disease at the time of diagnosis and a paucity of effective drugs available to treat advanced tumours. Despite a greater understanding of the genetic
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