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Developing agonistic therapeutic strategies for lung cancer based on synthetic lethal oncogene interactions

Developing agonistic therapeutic strategies for lung cancer based on synthetic lethal oncogene interactions
基于合成致死性癌基因相互作用开发肺癌激动性治疗策略
批准号：
345188
负责人：
Lockwood William W
金额：
$55.69万
依托单位：
BC Cancer, part of PHSA (Vancouver)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-03-01 至 2021-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=345188&lang=en
关键词：
Agonists Drug Discovery Egfr Functional Genomics Kras Lung Cancer Mouse Models Oncogenes Proteomics Targeted Therapeutics

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中文摘要
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英文摘要
Lung cancer is the leading cause of cancer mortality worldwide, suffering from a late stage of disease at the time of diagnosis and a paucity of effective drugs available to treat advanced tumours. Despite a greater understanding of the genetic basis of l
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