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The role of myocardin-related transcription factor (MRTF) in polycystic kidney disease

The role of myocardin-related transcription factor (MRTF) in polycystic kidney disease
心肌素相关转录因子(MRTF)在多囊肾病中的作用
批准号:
444106
负责人:
Kapus Andras
金额:
$60.75万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-04-01 至 2026-04-01

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中文摘要
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英文摘要
Polycystic kidney disease (PKD) is the most common inherited disorder of the kidney, affecting 1 in every 500 people. The vast majority of PKD cases are caused by a mutation or loss of one of two proteins, polycytsin 1 or 2. These proteins are located in
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Myocardin-related transcription factor (MRTF) and serum response factor (SRF) are constituents and key regulators of the primary cilium
  • 批准号:
    389251
  • 项目类别:
    Operating Grants
  • 资助金额:
    $50.16万
  • 财政年份:
    2018
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    Kapus Andras
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Topical susceptibility to TGF-beta: a new concept and key mechanism in myofibroblast generation
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    $48.84万
  • 财政年份:
    2013
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Fate-determining mechanisms in the epithelium during fibrogenesis: the role of cell contacts
  • 批准号:
    199847
  • 项目类别:
    Operating Grants
  • 资助金额:
    $47.1万
  • 财政年份:
    2010
  • 负责人:
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  • 依托单位:
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