Exploiting the synthetic-lethal vulnerabilities of stem cells and cancer cells with eroded telomeres
Exploiting the synthetic-lethal vulnerabilities of stem cells and cancer cells with eroded telomeres
批准号:
445608
负责人:
Harrington Lea A
金额:
$64.09万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-04-01 至 2026-04-01
中文摘要
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英文摘要
Stem cells are the cells that can replenish themselves or differentiate, and they generate and maintain all tissue-specific functions in adults. Stem cells share certain properties in common with tumor cells, including shortened chromosome ends (telomeres
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会议论文
Genetic and chemical ablation of senescent cells that result from age-dependent telomere erosion
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批准号:398885
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项目类别:Operating Grants
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资助金额:$32.68万
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财政年份:2018
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负责人:Harrington Lea A
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依托单位:
Telomere instability transforms differentiated stem cells into teratomas: implications for aging and disease
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批准号:347300
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负责人:Harrington Lea A
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依托单位:
Telomere integrity and stability of the differentiated state
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批准号:293207
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项目类别:Operating Grants
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资助金额:$58.13万
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财政年份:2013
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负责人:Harrington Lea A
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依托单位:
国内基金
海外基金
中国北方人群肺癌患者Cancer/Testis抗原表达谱绘制表位鉴定及功能性抗原特异性CTL制备研究
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批准号:81673007
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项目类别:面上项目
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资助金额:54.0万元
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批准年份:2016
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负责人:金时
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依托单位: