Intravital imaging of COVID-19 lungs to visualize pathogenic differences between SARS-CoV-2 variants of concern

对 COVID-19 肺部进行活体成像，以可视化所关注的 SARS-CoV-2 变体之间的致病差异

• 批准号: 449019
• 负责人: Kubes Paul
• 金额: $ 36.41万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-04-01 至 2022-04-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449019&lang=en
• 关键词: Brain; Endothelium; Heart; Imaging; Innate Immunity; Lungs; Neutrophils; Platelets; Sars-Cov2; Variants Of Concern

One of the most enigmatic features of SARS-CoV-2 infection is the clinical observation that some individuals have a mild infection that does not require any medical treatment, while others develop severe Coronavirus Disease (COVID) that results in hospita

SARS-CoV-2感染最神秘的特征之一是临床观察，一些人感染轻微，不需要任何治疗，而另一些人发展成严重的冠状病毒病(COVID)，导致住院治疗。