Chemokines and chemoattractants: a hierarchy of signals to allow neutrophil chemotaxis to sites of infection

趋化因子和趋化剂：允许中性粒细胞趋化至感染部位的信号层次

• 批准号: 190259
• 负责人: Kubes Paul
• 金额: $ 60.89万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=190259&lang=en
• 关键词: Cell Biology; Chemotaxis; Infection; Inflammation; Neutrophil; Signaling

Our first line of defense against bacteria and other invading organisms are white cells called neutrophils. To find these bacteria, the neutrophils must follow cues or road signs provided by our own immune system called chemokines. However, when in clos

我们抵御细菌和其他入侵生物的第一道防线是一种叫做中性粒细胞的白细胞。为了找到这些细菌，中性粒细胞必须遵循我们自身免疫系统提供的线索或路标，即趋化因子。然而，当接近时