A Tale of Two Resident Lung Macrophages and Their Biology In Health and Disease

两种常驻肺巨噬细胞的故事及其在健康和疾病中的生物学

• 批准号: 444782
• 负责人: Kubes Paul
• 金额: $ 91.95万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-04-01 至 2026-04-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444782&lang=en
• 关键词: Bacteria; Flu; Gata6 Cavity Macrophages; In Vivo; Lung; Macrophages; Microbiome; Microscopy; Migration; Pleural Space

The lung is exposed to the external environment so we breath in some bacteria and noxious molecules with every breath. Most of these bacteria never reach the little sacs (alveoli) where oxygen is taken up but some bacteria always do. We use a special m

肺暴露在外部环境中，所以我们每次呼吸都会吸入一些细菌和有害分子。大多数细菌都无法到达吸收氧气的小囊（肺泡），但有些细菌总能到达。我们用一个特殊的m