Immunologic Functions of Acute Cardiac Allograft Rejection Biomarkers in Peripheral Blood Cells

外周血细胞中急性心脏同种异体移植排斥生物标志物的免疫功能

• 批准号: 206162
• 负责人: Lin David
• 金额: $ 5.1万
• 依托单位: St. Paul's Hospital, Vancouver
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=206162&lang=en
• 关键词: Biomarker; Cardiac Allograft Rejection; Cardiovascular Disease; Cardiovascular Pathology; Flow Cytometry; Immunophenotyping; Molecular Biology; Real-Time Polymerase Chain Reaction; Transplantation Immunology

After heart transplantation, recipient's immune system can recognize the transplanted heart, or cardiac allograft, as foreign and launch an immune response against it. This process can lead to acute cardiac rejection (ACR) episodes, which occurs in 20-50%

心脏移植后，受体的免疫系统可以识别移植的心脏或心脏同种异体移植物，并对其产生免疫反应，这一过程可导致急性心脏排斥反应（acute cardiac rejection，ACR），发生率为20-50%。