Neural mechanisms underlying the adaptive plasticity of human locomotion

人类运动适应性可塑性背后的神经机制

• 批准号: RGPIN-2018-06184
• 负责人: Bouyer, Laurent
• 金额: $ 3.42万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=714145
• 关键词: Neural; mechanisms; underlying; adaptive; plasticity

The aim of the present work is to better understand the adaptive capacity/learning ability of the neural control of human locomotion. In the proposed experiments, locomotor control will be challenged by having subjects walk on a treadmill in altered force environments (“force fields”) generated by a custom-made robotized orthosis. In order to walk normally in the presence of the force field, participants need to temporarily modify their stereotypic muscle activation pattern, an experimental model of motor learning. Over the next five years, the following 3 objectives will be addressed:

本工作的目的是更好地了解人类运动的神经控制的自适应能力/学习能力。在拟议的实验中，运动控制将受到挑战，让受试者在由定制的机器人矫形器产生的改变的力环境（“力场”）中在跑步机上行走。为了在力场的存在下正常行走，参与者需要暂时改变他们刻板的肌肉激活模式，这是一种运动学习的实验模型。在未来五年，将实现以下三个目标：