Bioavailability evaluation of new innovative formulations

新创新配方的生物利用度评估

• 批准号: 562749-2021
• 负责人: Fortier, Isabelle
• 金额: $ 0.91万
• 依托单位: Cégep de Lévis
• 依托单位国家: 加拿大
• 项目类别: Engage Plus Grants for Colleges
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=725068
• 关键词: Bioavailability; evaluation; new; innovative; formulations

Several active molecules derived from either elemental sources or complexes matrices such as plant and mushroom lack strong therapeutical potential because of their poor absorption and bioavailability upon being consumed. Folium Labs as developed drug delivery agents like hyaluronic acid. HA is an interesting agent as it is a macropolysaccharide naturally present in most tissues and body fluids that may fortunately, such limitations to be overcome. This Engage PLUS proposal is grounded on works performed during the proposed Engage project that permitted the demonstration of a very promising effect on hydrophobic and typically poorly bioavailable molecules. Facing the strong potential of its products, Folium Labs would now want to expand the understanding of the spectrum of molecules suited for its formulation gains in bioavailability. Folium Labs will gain key positioning indication regarding its products to better compare them with commercial competitors, develop new optimized products and secure more funding from investors.

几种来源于元素来源或络合物基质如植物和蘑菇的活性分子缺乏强大的治疗潜力，因为它们在食用时吸收和生物利用度差。作为开发的药物输送剂，如透明质酸。HA是一种令人感兴趣的试剂，因为它是天然存在于大多数组织和体液中的大多糖，幸运的是，这种限制可以被克服。该Engage PLUS提案基于在拟议的Engage项目期间进行的工作，该项目允许证明对疏水性和通常生物利用度较差的分子具有非常有希望的作用。面对其产品的强大潜力，ECOLABS现在希望扩大对适合其生物利用度配方增益的分子谱的理解。ESTLabs将获得有关其产品的关键定位指示，以更好地将其与商业竞争对手进行比较，开发新的优化产品，并从投资者那里获得更多资金。