Bio-Synthetic Interfaces

生物合成界面

• 批准号: CRC-2016-00178
• 负责人: Cerruti, Marta
• 金额: $ 6.68万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=729847
• 关键词: Bio; Synthetic; Interfaces

Each year, 3.5 million people suffer from fractures or cancer that require bone grafts to be fixed. These are usually performed by transferring bone from a healthy location onto the injured site, a painful and risky procedure. Despite this, bone grafts are still the clinic golden standard, since no artificial material matches their performance. Cartilage injuries affect 70% of the senior population, and are similarly challenging to treat. This program addresses both of these challenges, by developing a number of platforms aimed at improving bone or cartilage regeneration with innovative biomimetic approaches based on material surface modification.

每年有350万人患有骨折或癌症，需要进行骨移植修复。这些手术通常是通过将骨骼从健康部位转移到受伤部位来进行的，这是一个痛苦和危险的过程。尽管如此，骨移植仍然是临床的黄金标准，因为没有人工材料能与其性能相匹配。软骨损伤影响了70%的老年人口，治疗起来同样具有挑战性。该计划通过开发一系列旨在通过基于材料表面修改的创新仿生方法来改善骨或软骨再生的平台，来应对这两个挑战。