课题基金 / 基金详情

Rationally designed ribozymes switched-on by nucleotide repeat extensions as potential tools of genetic therapy for repeat expansion disorders.

Rationally designed ribozymes switched-on by nucleotide repeat extensions as potential tools of genetic therapy for repeat expansion disorders.
合理设计的核酶通过核苷酸重复延伸开启，作为重复扩张疾病基因治疗的潜在工具。
批准号：
464593
负责人：
Rouleau Guy A
金额：
$7.29万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-03-01 至 2023-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=464593&lang=en
关键词：
Amyotrophic Lateral Sclerosis Gene Silencing Huntington Disease Machado-Joseph Disease Neurogenerative Disease Oculopharyngeal Muscular Dystrophy Pseudoknot Repeat Expansion Ribozyme Trinucleotide Repeats

项目摘要

项目成果

Rouleau Guy A的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Over 40 diseases, including incurable and fatal neurodegenerative diseases such as ALS, are caused by the expansion of repetitive sequences in the genome. Beyond a certain size, these expansions cause problems in the cells and the body, leading to disease
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Rationally designed ribozymes switched-on by nucleotide repeat extensions as potential tools of genetic therapy for repeat expansion disorders.
  • 批准号：
    479481
  • 项目类别：
    Operating Grants
  • 资助金额：
    $77.74万
  • 财政年份：
    2023
  • 负责人：
    Rouleau Guy A
  • 依托单位：
    McGill University
Advancing our understanding of essential tremor genetics and biology
  • 批准号：
    483432
  • 项目类别：
    Operating Grants
  • 资助金额：
    $7.29万
  • 财政年份：
    2023
  • 负责人：
    Rouleau Guy A
  • 依托单位：
    McGill University
Advancing our understanding of essential tremor genetics and biology
  • 批准号：
    489526
  • 项目类别：
    Operating Grants
  • 资助金额：
    $63.25万
  • 财政年份：
    2023
  • 负责人：
    Rouleau Guy A
  • 依托单位：
    McGill University
Rationally designed ribozymes switched-on by nucleotide repeat extensions as potential tools of genetic therapy for repeat expansion disorders.
  • 批准号：
    472596
  • 项目类别：
    Operating Grants
  • 资助金额：
    $7.29万
  • 财政年份：
    2022
  • 负责人：
    Rouleau Guy A
  • 依托单位：
    McGill University
海外基金