Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
基本信息
- 批准号:RGPIN-2016-06232
- 负责人:
- 金额:$ 4.52万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2021
- 资助国家:加拿大
- 起止时间:2021-01-01 至 2022-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Abnormal Epigenetic Adaptation; Chromatin Immunoprecipitation & Sequencing (ChIP-Seq); DNA Methylation; DNMT1 (DNA methyltransferase-1); Early Embryogenesis; Epigenetic Cross-Talk; Epigenetic Reprogramming; Histone Modifications; Mouse Embryonic Stem Cells; Reduced Representation Bisulfite Sequencing (RRBS)
异常表观遗传适应;染色质免疫沉淀和测序(ChIP-Seq); DNA甲基化; DNMT 1(DNA甲基转移酶-1);早期胚胎发生;表观遗传串扰;表观遗传重编程;组蛋白修饰;小鼠胚胎干细胞;还原亚硫酸氢盐测序(RRBS)
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
McGraw, Serge其他文献
Spatiotemporal expression of transcriptional regulators in concert with the maternal-to-embryonic transition during bovine in vitro embryogenesis
- DOI:
10.1530/rep-08-0077 - 发表时间:
2009-01-01 - 期刊:
- 影响因子:3.8
- 作者:
Vigneault, Christian;McGraw, Serge;Sirard, Marc-Andre - 通讯作者:
Sirard, Marc-Andre
Clearance of defective muscle stem cells by senolytics restores myogenesis in myotonic dystrophy type 1.
- DOI:
10.1038/s41467-023-39663-3 - 发表时间:
2023-07-19 - 期刊:
- 影响因子:16.6
- 作者:
Conte, Talita C. C.;Duran-Bishop, Gilberto;Orfi, Zakaria;Mokhtari, Ines;Deprez, Alyson;Cote, Isabelle;Molina, Thomas;Kim, Tae-Yeon;Tellier, Lydia;Roussel, Marie-Pier;Maggiorani, Damien;Benabdallah, Basma;Leclerc, Severine;Feulner, Lara;Pellerito, Ornella;Mathieu, Jean;Andelfinger, Gregor;Gagnon, Cynthia;Beausejour, Christian;McGraw, Serge;Duchesne, Elise;Dumont, Nicolas A. A. - 通讯作者:
Dumont, Nicolas A. A.
Sex-based disparities in DNA methylation and gene expression in late-gestation mouse placentas.
- DOI:
10.1186/s13293-023-00577-w - 发表时间:
2024-01-06 - 期刊:
- 影响因子:7.9
- 作者:
Legault, Lisa-Marie;Breton-Larrivee, Melanie;Langford-Avelar, Alexandra;Lemieux, Anthony;McGraw, Serge - 通讯作者:
McGraw, Serge
Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis.
对MYST4组蛋白乙酰转移酶的研究及其参与哺乳动物的配子发生。
- DOI:
10.1186/1471-213x-7-123 - 发表时间:
2007-11-02 - 期刊:
- 影响因子:0
- 作者:
McGraw, Serge;Morin, Guillaume;Vigneault, Christian;Leclerc, Pierre;Sirard, Marc-Andre - 通讯作者:
Sirard, Marc-Andre
Temporal expression of factors involved in chromatin remodeling and in gene regulation during early bovine in vitro embryo development
- DOI:
10.1530/rep-06-0251 - 发表时间:
2007-03-01 - 期刊:
- 影响因子:3.8
- 作者:
McGraw, Serge;Vigneault, Christian;Sirard, Marc-Andre - 通讯作者:
Sirard, Marc-Andre
McGraw, Serge的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('McGraw, Serge', 18)}}的其他基金
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2020
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2018
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2017
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2016
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
相似海外基金
Epigenetic regulation of inherited aortic disease
遗传性主动脉疾病的表观遗传调控
- 批准号:
23K08279 - 财政年份:2023
- 资助金额:
$ 4.52万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2020
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2019
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Defining the epigenetic origins of maternally inherited disease.
定义母系遗传疾病的表观遗传起源。
- 批准号:
nhmrc : GNT1144966 - 财政年份:2018
- 资助金额:
$ 4.52万 - 项目类别:
Project Grants
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2018
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Defining the epigenetic origins of maternally inherited disease.
定义母系遗传疾病的表观遗传起源。
- 批准号:
nhmrc : 1144966 - 财政年份:2018
- 资助金额:
$ 4.52万 - 项目类别:
Project Grants
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2017
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Mechanisms of Inherited Epigenetic Dysregulation in Early Embryonic Development
早期胚胎发育中遗传性表观遗传失调的机制
- 批准号:
RGPIN-2016-06232 - 财政年份:2016
- 资助金额:
$ 4.52万 - 项目类别:
Discovery Grants Program - Individual
Determining the impact of inherited epigenetic information on development and disease
确定遗传性表观遗传信息对发育和疾病的影响
- 批准号:
nhmrc : 1051223 - 财政年份:2013
- 资助金额:
$ 4.52万 - 项目类别:
Project Grants
Metabo-epigenetic regulatory circuits of heart disease caused by inherited and acquired lipid accumulation (A01)
遗传性和获得性脂质积累引起的心脏病的代谢表观遗传调节回路(A01)
- 批准号:
508070962 - 财政年份:
- 资助金额:
$ 4.52万 - 项目类别:
Collaborative Research Centres














{{item.name}}会员




