Thoracic and Lumbar Spine Biomechanics

胸椎和腰椎生物力学

• 批准号: RGPIN-2019-06832
• 负责人: Drake, Janessa
• 金额: $ 2.91万
• 依托单位: York University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=739129
• 关键词: Thoracic; Lumbar; Spine; Biomechanics

Appropriate neuromuscular control and musculoskeletal responses of the thoracic and lumbar spine are essential to complete work and everyday tasks without injury. Labour injury statistics across Canada show low back pain (LBP) consistently represented the largest number of workplace related musculoskeletal disorder (WRMSD) claims (~18%) and had a total costs over $2 billion/year in 2014. We know that twist in the spine is a significant risk factor for LBP development is suspected to still be associated with ~60% of low back injuries. My earlier research contributed to the evidence of posture-dependent injury mechanics, but how these present in-vivo is not fully understood. If you consider the incidence of LBP increases with age, and that the Statistics Canada estimate that by 2027 30% of the Canadian population will be over 55 years, we must improve the knowledge about spine function now. Fatigue has been shown to occur at different rates and magnitudes in low back muscles (differently for males and females), likely by interfering with the neuromuscular control of trunk movement. My program examines the structure, control, and function of the thoracic and lumbar spine, considers the effects of age, sex, and fatigue, to characterize the mechanisms underlying how we respond to a range of loading exposures. The foundational knowledge I generate deepens our understanding of the spine; my aim is to help reduce WRMSDs and costs to Canadians. The short term objectives of my NSERC funded research program are to quantify and evaluate the thoracic and lumbar spine neuromuscular control and musculoskeletal responses to exposures that have been identified as workplace risk factors, using motion analysis, electromyography (EMG), magnetic resonance imaging (MRI) and ultrasound methods.My research has improved the understanding of in-vivo lumbar spine morphology and function in response to twist; characterization of the thoracic spine; movement strategy adaptations in complex loading and prolonged sitting.   The novel methods we developed/are developing to measure in-vivo spine segmental kinematics (including twist) and muscle blood perfusion respectively, have huge potential to rapidly increase our understanding of twist as a dangerous risk factor occurring in workplaces. The empirical data and understanding of spine function generated from my program can be incorporated into existing thoracic and lumbar spine models and can set parameters for in-vitro spine testing (to test injury mechanism theory). By reaching my research goals, developing thriving HQP and research team, and publishing in excellent journals, my research program will continue to make new discoveries and have a major impact on biomechanics and ergonomic fields. My program is the only one in Canada to focus on using these approaches on those objectives to identify and understand both the potential, and existing spine injury mechanisms.

适当的神经肌肉控制和胸腰椎肌肉骨骼反应是完成工作和日常任务而不受伤的必要条件。加拿大的工伤统计数据显示，腰痛（LBP）一直是与工作场所相关的肌肉骨骼疾病（WRMSD）索赔的最大比例（约18%），2014年的总成本超过20亿美元/年。我们知道脊柱扭曲是腰痛发展的一个重要危险因素，被怀疑仍与约60%的腰背损伤有关。我早期的研究为姿势依赖的损伤机制提供了证据，但这些机制在体内是如何存在的还不完全清楚。如果你考虑到腰痛的发病率随着年龄的增长而增加，并且加拿大统计局估计到2027年，30%的加拿大人口将超过55岁，我们现在必须提高对脊柱功能的认识。疲劳已被证明在腰背部肌肉中以不同的速率和程度发生（男女不同），可能是由于干扰躯干运动的神经肌肉控制。我的项目检查了胸椎和腰椎的结构、控制和功能，考虑了年龄、性别和疲劳的影响，以表征我们对一系列负荷暴露的反应机制。我所产生的基础知识加深了我们对脊柱的理解；我的目标是帮助减少wrmsd和加拿大人的成本。我的NSERC资助的研究项目的短期目标是量化和评估胸椎和腰椎神经肌肉控制和肌肉骨骼对暴露的反应，这些暴露已被确定为工作场所的危险因素，使用运动分析，肌电图（EMG），磁共振成像（MRI）和超声方法。我的研究提高了对体内腰椎形态和功能对扭转的反应的理解；胸椎的特征；复杂负荷和长时间坐着的运动策略适应。我们开发/正在开发的分别测量体内脊柱节段运动学（包括扭转）和肌肉血液灌注的新方法具有巨大的潜力，可以迅速增加我们对扭转作为工作场所发生的危险因素的理解。我的项目产生的经验数据和对脊柱功能的理解可以纳入现有的胸椎和腰椎模型，并可以为体外脊柱试验设定参数（以验证损伤机制理论）。通过实现我的研究目标，发展蓬勃的HQP和研究团队，并在优秀期刊上发表文章，我的研究项目将继续有新的发现，并在生物力学和人体工程学领域产生重大影响。我的项目是加拿大唯一一个专注于使用这些方法来识别和理解潜在的和现有的脊柱损伤机制的项目。