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Characterization of PIKfyve as novel therapeutic target in clear cell Renal Cell Carcinoma

Characterization of PIKfyve as novel therapeutic target in clear cell Renal Cell Carcinoma
PIKfyve 作为透明细胞肾细胞癌新治疗靶点的表征
批准号：
472410
负责人：
Turcotte Sandra
金额：
$7.29万
依托单位：
Universit de Moncton (New Brunswick)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
已结题
起止时间：
2022-09-01 至 2023-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472410&lang=en
关键词：
Kidney Cancer Lysosomes Molecular Biology Pikfyve Small Molecules Targeted Therapy Tumor Suppressor Genes

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中文摘要
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英文摘要
Kidney cancer is the 9th most common type of cancer diagnosed in the country. It affects more men than women by a 2:1 ratio and the average age of diagnosis is 64 years. These tumors are asymptomatic and 30% of patients present metastases at diagnosis. Th
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Exploiting synthetic lethality in Renal Cell Carcinoma: Targeting the loss of the von Hippel-Lindau tumor suppressor gene through autophagy for the development of anticancer therapy
Targeting the loss of the von Hippel-Lindau tumor suppressor gene at a late-stage of autophagy for the development of anticancer therapy
  • 批准号：
    264837
  • 项目类别：
    Salary Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2012
  • 负责人：
    Turcotte Sandra
  • 依托单位：
    Universit de Moncton (New Brunswick)
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