A gas chromatography tandem mass spectrometry (GC-MS/MS) system for trace contaminant of emerging concern (TCEC) research

所要求的气相色谱-串联质谱仪(GC-MS/MS)系统支持三个环境工程的迫切设备要求。英语学院的教职员工。不列颠哥伦比亚大学S·奥卡纳根校区。该小组旨在了解新出现的关注的遗留痕量污染物(TCEC；例如，药品/个人护理产品、阻燃剂、杀虫剂、二恶英和呋喃)以及常规和高级水和废水处理厂(WWTP)工艺中的消毒副产品(DBPs)的命运/行为。至关重要的是，它们必须准确量化，以符合正在考虑的工厂污水和生物固体流扩建和新处理设施的法规。正在进行的项目的时机至关重要，因为温哥华大都会的液体废物服务部正在开发新的工厂(即北岸污水处理厂、西北兰利污水处理厂、爱奥纳岛污水处理厂)，并考虑升级其他两个现有工厂(即Lulu和Annacis Island污水处理厂的新厌氧消化器)。这将是未来15年近40亿美元的资本基础设施投资，关键决策可以通过IRC计划和所需的GC-MS/MS得到显著增强的结果来提供信息。该团队迫切需要一个具有高灵敏度的先进的GC-MS/MS系统，以获得准确的定量低限的化学、生物化学和环境化合物，根据欧盟和北美报告的TCEC和DBPS水平，最好是百万分之几(Ppb)或更低。对于我们现有的设备来说，这是目前不可能的。这些设备将支持培训高素质人员(HQP)，并支持许多工业和市政合作伙伴由于附近没有GC-MS/MS而无法实现的潜在项目和伙伴关系。我们校园缺乏GC-MS/MS已导致与奥卡纳根地区的工业合作伙伴(例如，北部和中部奥卡纳根地区、卑诗省第一民族卫生局)失去了多个合作机会，并导致重大研究中断，包括HQP未得到培训，以及学生毕业和出版延迟。三位副研究员目前监督约30名HQP，该仪器的培训潜力可高达50 HQP，包括SOE和科学院潜在用户团队中的研究人员。在校园内拥有GC-MS/MS设施将使几乎所有遗留的TCEC、DBPs和生化化合物(与现有的分析设施一起)能够高效、可重复和及时地进行定量。使用这种设备获得的技能将帮助总部在私营和公共部门找到各种工程和科学学科的工作，涉及环境、生物化学和药物样本的分析(例如，AECOM、Bureau Veritas、ALS实验室)。

The requested gas chromatography tandem mass spectrometry (GC--MS/MS) system supports an imperative equipment requirement of three Environmental Eng. faculty in the School of Eng. (SoE) at the University of British Columbia (UBC)'s Okanagan Campus (UBCO). The team aims to understand the fate/behaviour of legacy trace contaminants of emerging concern (TCEC; e.g., pharmaceuticals/personal care products, flame retardants, pesticides, dioxins, and furans) and disinfection-by-products (DBPs) in conventional and advanced water and wastewater treatment plant (WWTP) processes. It is vital that they are accurately quantified to comply with regulations under consideration for plant effluent and biosolids streams for expansions and new treatment facilities. Timing of on-going projects is crucial as Metro Vancouver's Liquid Waste Services Department is developing new plants (i.e., North shore WWTP, Northwest Langley WWTP, Iona Island WWTP) and considering upgrades to the other two existing plants (i.e., new anaerobic digesters at Lulu and Annacis Island WWTPs). This is approaching $4 billion of capital infrastructure investment over the next 15 years, and key decisions can be informed by the findings significantly enhanced through the IRC program and the requested GC-MS/MS. The team urgently needs an advanced GC--MS/MS system with high sensitivity to obtain accurate quantification of chemical, biochemical, and environmental compounds at low limit of quantitation, preferable parts per billion (ppb) or lower as per European Union and North American reporting level of TCEC and DBPs. This is currently impossible with our existing equipment. The equipment will support the training of highly qualified personnel (HQP) and enable the potential projects and partnerships that are out of reach for many industrial and municipal partners due to the unavailability of a GC-MS/MS in the vicinity. The lack of a GC-MS/MS on our campus has resulted in the loss of multiple collaboration opportunities with industrial partners in the Okanagan (e.g., Regional Districts of the North and Central Okanagan, BC First Nations Health Authority) and has caused significant research interruptions, including HQP not being trained and delays to students' graduations and publications. The three co-investigators currently supervise approximately 30 HQP and the training potential of the instrument can be as high as 50 HQP including the researchers in the teams of the potential users within the SoE and the Faculty of Sciences. Having an GC-MS/MS facility on Campus will allow the efficient, repeatable, and timely quantification of nearly all legacy TCEC, DBPs and biochemical compounds (in tandem with existing analytical facilities). The skills gained with this equipment will help HQP to secure jobs in the private and public sector in various engineering and science disciplines dealing with analysis of environmental, biochemical and pharmaceutical samples (e.g. AECOM, Bureau Veritas, ALS Labs).