Stress-induced relapse following voluntary abstinence: model characterization and critical neural pathways

自愿戒烟后压力诱发的复发：模型特征和关键神经通路

• 批准号: 468024
• 负责人: Shalev Uri
• 金额: $ 43.47万
• 依托单位: Concordia University (Montreal, Quebec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468024&lang=en
• 关键词: Abstinence; Addiction; Drug Abuse; Negative Consequences; Punishment; Rat; Relapse; Stress

A major difficulty in the treatment of drug addiction is the high rate of relapse following periods of abstinence. There is strong evidence that exposure to stressful incidents (like an argument with one's spouse) is associated with subsequent drug relaps

戒毒治疗的一个主要困难是戒断期后复吸率很高。有强有力的证据表明，暴露于压力事件（如与配偶的争吵）与随后的药物复发有关