High Vacuum Carbon and Metal Coater for Electron Microscopy Samples
用于电子显微镜样品的高真空碳和金属镀膜机
基本信息
- 批准号:RTI-2022-00591
- 负责人:
- 金额:$ 7.07万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Research Tools and Instruments
- 财政年份:2021
- 资助国家:加拿大
- 起止时间:2021-01-01 至 2022-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
A high vacuum carbon and metal coater is essential equipment to prepare samples for both transmission electron microscopy (TEM) and scanning electron microscopy (SEM) applications. TEM and SEM are used by the co-applicants in the UBC Bioimaging Facility (BIF) to resolve plant cell, food products, and bioproducts structures at the nanometer scale. Funding is requested to purchase a new high vacuum coater that has three capabilities: 1) to deposit ultra-thin carbon films at uniform thickness crucial for SEM and electron diffraction X-ray (EDX) analysis, as well as stabilizing sample-supporting films on TEM grids; 2) to coat samples with metal for high-resolution scanning electron microscopy (SEM); and 3) to make TEM sample grids hydrophilic to spread aqueous samples, such as cellulose nanocrystals and nanofibrils, uniformly over the grid. The equipment will be support BIF's one SEM and three TEMs. The ability produce high-quality carbon and metal coated thin films that would meet our urgent research needs to prepare samples for high-resolution SEM, EDX and TEM analysis on non-conductive nanoscale samples at UBC Vancouver. The Samuels lab (BOTA) will use the high vacuum carbon and metal coater to prepare plant samples for SEM, both in developing poplar wood and in the trichomes of cannabis plants. In addition, for high-resolution studies of cannabis trichomes that produce large quantities of THC, the Samuels lab requires the coater in order to reinforce TEM grids to support samples during electron tomography. The Singh lab (Faculty of Land and Food Systems) uses SEM to examine a variety of bioactive compounds such as recombinant proteins, food additives and spray dried microparticles. In order to investigate the distribution pattern of metallic nanoparticles in the microsphere structure, the high vacuum coater is required to coat samples with ultra-thin carbon and metal at uniform thickness for the ultrahigh-resolution analysis of SEM and EDX. The Foster lab (CHBE) works on development of bionanomaterials that are polymers and nanocomposites. The carbon and metal coating are their routine sample preparation workflow to characterize these new materials using SEM and TEM. Purchase of this equipment will benefit not only the co-applicants' labs, but the many future researchers who conduct high-resolution SEM and TEM analysis at the UBC Bioimaging facility. As BIF is a campus-wide shared research facility, this equipment is widely used, e.g. BIF's previous low vacuum coater at the facility was used by 12 HQP from 10 different UBC research groups last year. Unfortunately, the old coating equipment is now out of order and not repairable.Two dedicated staff at the facility will provide training and support to HQPs for ultrathin coating on their samples. A delay in purchasing the high vacuum coater could negatively impact the thesis and research progress of the estimated 10-20 HQPs relying on this equipment.
高真空碳和金属镀膜机是制备透射电子显微镜(TEM)和扫描电子显微镜(SEM)应用样品的必要设备。TEM和SEM被UBC生物成像设备(BIF)的共同申请人用于在纳米尺度上解析植物细胞、食品和生物产品结构。需要资金购买一台新的高真空镀膜机,该镀膜机有三种能力:(1)存款厚度均匀的超薄碳膜,这对扫描电镜和电子衍射X射线分析至关重要,并稳定TEM网格上的样品支撑膜;(2)为高分辨率扫描电子显微镜用样品涂上金属;和3)使TEM样品网格亲水以在网格上均匀地散布含水样品,例如纤维素纳米晶体和纳米原纤维。该设备将支持BIF的一个SEM和三个TEM。生产高质量碳和金属涂层薄膜的能力,将满足我们的迫切研究需要,为在UBC温哥华对非导电纳米级样品进行高分辨率SEM,EDX和TEM分析准备样品。 Samuels实验室(BOTA)将使用高真空碳和金属涂布机来制备用于SEM的植物样品,无论是在开发白杨还是大麻植物的毛状体中。此外,对于产生大量THC的大麻毛状体的高分辨率研究,Samuels实验室需要涂布机以加强TEM网格,以在电子断层扫描期间支持样品。辛格实验室(土地和食品系统学院)使用SEM检查各种生物活性化合物,如重组蛋白质,食品添加剂和喷雾干燥微粒。为了研究金属纳米颗粒在微球结构中的分布规律,需要高真空镀膜机在样品上涂上均匀厚度的超薄碳和金属,以进行SEM和EDX的超高分辨率分析。福斯特实验室(CHBE)致力于开发生物纳米材料,即聚合物和纳米复合材料。碳和金属涂层是他们使用SEM和TEM表征这些新材料的常规样品制备工作流程。 购买该设备不仅有利于共同申请人的实验室,而且有利于在UBC生物成像设施进行高分辨率SEM和TEM分析的许多未来研究人员。由于BIF是一个校园范围内的共享研究设施,这种设备被广泛使用,例如,BIF以前的低真空镀膜机在该设施被使用12 HQP从10个不同的UBC研究小组去年。不幸的是,旧的涂层设备现在出了故障,无法修复。工厂的两名专门工作人员将为HQP提供培训和支持,以便在样品上进行涂层。 延迟购买高真空镀膜机可能会对依赖该设备的估计10-20个HQP的论文和研究进展产生负面影响。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Samuels, Anne其他文献
Samuels, Anne的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Samuels, Anne', 18)}}的其他基金
Uncovering the Mysteries of Cannabis: How Trichomes of Cannabis Produce their Unique Metabolites.
揭开大麻的奥秘:大麻毛状体如何产生其独特的代谢物。
- 批准号:
RGPIN-2019-04592 - 财政年份:2022
- 资助金额:
$ 7.07万 - 项目类别:
Discovery Grants Program - Individual
Uncovering the Mysteries of Cannabis: How Trichomes of Cannabis Produce their Unique Metabolites.
揭开大麻的奥秘:大麻毛状体如何产生其独特的代谢物。
- 批准号:
RGPIN-2019-04592 - 财政年份:2021
- 资助金额:
$ 7.07万 - 项目类别:
Discovery Grants Program - Individual
Uncovering the Mysteries of Cannabis: How Trichomes of Cannabis Produce their Unique Metabolites.
揭开大麻的奥秘:大麻毛状体如何产生其独特的代谢物。
- 批准号:
RGPIN-2019-04592 - 财政年份:2020
- 资助金额:
$ 7.07万 - 项目类别:
Discovery Grants Program - Individual
Uncovering the Mysteries of Cannabis: How Trichomes of Cannabis Produce their Unique Metabolites.
揭开大麻的奥秘:大麻毛状体如何产生其独特的代谢物。
- 批准号:
RGPIN-2019-04592 - 财政年份:2019
- 资助金额:
$ 7.07万 - 项目类别:
Discovery Grants Program - Individual
Increasing Versatility in a Multi-User Laser Scanning Confocal Microscope
提高多用户激光扫描共焦显微镜的多功能性
- 批准号:
RTI-2019-00409 - 财政年份:2018
- 资助金额:
$ 7.07万 - 项目类别:
Research Tools and Instruments
相似国自然基金
一碳代谢(One carbon metabolism)介导上调的 PD1/PDL1 驱动
肿瘤免疫逃逸
- 批准号:2024JJ9491
- 批准年份:2024
- 资助金额:0.0 万元
- 项目类别:省市级项目
三维碳纳米材料(nano-carbon@ZSM-5)的制备及应用
- 批准号:
- 批准年份:2022
- 资助金额:30 万元
- 项目类别:青年科学基金项目
理论预言的三维碳同素异构体T-carbon的制备及其物性的实验深入研究
- 批准号:
- 批准年份:2020
- 资助金额:58 万元
- 项目类别:面上项目
绿色热量运动驱动的G-Carbon系统碳生产力发展研究
- 批准号:51976085
- 批准年份:2019
- 资助金额:56.0 万元
- 项目类别:面上项目
金属有机框架ZIF-67基Co@Carbon膜催化反应器设计、制备及其用于丙烷催化脱氢反应过程强化研究
- 批准号:21878100
- 批准年份:2018
- 资助金额:66.0 万元
- 项目类别:面上项目
乳腺癌发生发展过程中巨噬细胞glucose-serine-glycine-1-carbon代谢异常对肿瘤恶性进展的影响及其分子机制的研究
- 批准号:81730077
- 批准年份:2017
- 资助金额:290.0 万元
- 项目类别:重点项目
多级g-C3N4/Carbon复合物的合成及可见光光催化研究
- 批准号:51402147
- 批准年份:2014
- 资助金额:25.0 万元
- 项目类别:青年科学基金项目
黄、东海沉积物中碳黑(Black Carbon)的地球化学研究
- 批准号:40576039
- 批准年份:2005
- 资助金额:40.0 万元
- 项目类别:面上项目
相似海外基金
SBIR Phase I: Optimizing Composition of Novel Molten Alkali Metal Borates for Carbon Dioxide Capture
SBIR 第一阶段:优化用于二氧化碳捕获的新型熔融碱金属硼酸盐的成分
- 批准号:
2332658 - 财政年份:2024
- 资助金额:
$ 7.07万 - 项目类别:
Standard Grant
PFI (MCA): Hydrogen and Solid Carbon Production with Electrified Methane Pyrolysis in Zeolite-Protected, Metal Membrane Reactor
PFI (MCA):在沸石保护的金属膜反应器中通过带电甲烷热解生产氢气和固体碳
- 批准号:
2325780 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Standard Grant
Innovative carbon-metal nanohybrids (CMNs) for simultaneous removal of heavy metals and radionuclides from contaminated water: experimental investigation & utilization in membrane unit
用于同时去除污染水中的重金属和放射性核素的创新碳-金属纳米杂化物(CMN):实验研究
- 批准号:
23K17055 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Oxygen reduction reaction (ORR) in fuel cells on carbon-based metal-free electrocatalysts by first-principles multiscale simulations.
通过第一原理多尺度模拟,在碳基无金属电催化剂上进行燃料电池中的氧还原反应(ORR)。
- 批准号:
22KJ2131 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Grant-in-Aid for JSPS Fellows
Ethylene Selective Carbon Dioxide Reduction Reaction on Redox Active Polymer/Metal Interface with Atomic Hydrogens
氧化还原活性聚合物/金属界面与原子氢的乙烯选择性二氧化碳还原反应
- 批准号:
23KJ0227 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Grant-in-Aid for JSPS Fellows
RUI: CAS: Novel Carbon Nanosphere Encapsulated Bimetallic Catalysts and Metal-CeO2 Interfaces for CO2 Conversion to Value-added Chemicals
RUI:CAS:新型碳纳米球封装双金属催化剂和金属-CeO2 界面,用于将二氧化碳转化为增值化学品
- 批准号:
2247399 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Standard Grant
CAREER: 3D Printed Carbon-Metal Nanohybrid Aerogels for Highly Efficient Adsorptive/Catalytic Removal of PFASs
职业:3D 打印碳金属纳米杂化气凝胶,用于高效吸附/催化去除 PFAS
- 批准号:
2331082 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Continuing Grant
Explore the Origin of the Oxygen Reduction Performance of Atomically Dispersed Transition Metal-Nitrogen-Carbon (M-N-C) Catalysts
探索原子分散过渡金属-氮-碳(M-N-C)催化剂氧还原性能的起源
- 批准号:
23K13703 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
MIX-MOXes - Mixed Metal Oxides Energy Stations for zero-carbon thermal energy generation with integrated heat storage
MIX-MOXes - 混合金属氧化物能源站,用于通过集成热存储实现零碳热能发电
- 批准号:
EP/X000249/1 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Research Grant
Development of non-noble-metal catalysts using biomass-derived carbon for biohydrogen production
利用生物质衍生的碳开发用于生物制氢的非贵金属催化剂
- 批准号:
22KF0034 - 财政年份:2023
- 资助金额:
$ 7.07万 - 项目类别:
Grant-in-Aid for JSPS Fellows