Main-Group Catalysis and Sustainable Chemistry

主族催化和可持续化学

• 批准号: CRC-2021-00020
• 负责人: Caputo, Christopher
• 金额: $ 5.46万
• 依托单位: York University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=747340
• 关键词: Main; Group; Catalysis; Sustainable; Chemistry

Chemicals make up the core building blocks for all products that our society relies on (for example, pharmaceuticals for health, agrochemicals for food, advanced materials for microchips, dyes for cosmetics, just to name a few). Unfortunately, the production of chemicals is an energy intensive and polluting process, consuming ~10% of global oil and gas supplies and accounting for ~15% of global emissions. The challenges we face demand a significantly more sustainable approach towards creating these building blocks, and chemists are uniquely positioned to provide solutions. Dr. Caputo's research program will tackle this problem through a two-pronged approach. The first is developing greener catalysts to create these desired materials - a catalyst is a molecule that lowers the barriers to a chemical reaction, allowing them to proceed using less energy. Unfortunately, many industrial catalysts are based off precious metals, which are rare, expensive, and unsustainable. Dr. Caputo's research will develop alternatives using earth abundant main-group elements. Recent discoveries have found these metal-free alternatives are nearly as effective as their precious metal counterparts for several key reactions, including the hydrogenation of unsaturated substrates. His research also seeks to understand the fundamental reasons what makes these main-group catalysts effective and use this data to create superior systems. The second approach looks to develop value added molecules from renewable feedstocks, as opposed to the ubiquitously used petroleum feedstocks. This program will apply synthetic chemistry approaches towards specific natural products to develop a first of its kind long lasting personal products, initially targeting ultra long-lasting sun protection. These have the potential to revolutionize the personal care space and would undoubtedly result in significant IP protection and commercialization.

化学品构成了我们社会所依赖的所有产品的核心组成部分（例如，用于健康的药物，用于食品的农用化学品，用于微芯片的先进材料，用于化妆品的染料，仅举几例）。不幸的是，化学品的生产是一个能源密集型和污染的过程，消耗了全球石油和天然气供应的10%，占全球排放量的15%。我们所面临的挑战需要一种更加可持续的方法来创造这些构建模块，而化学家在提供解决方案方面具有独特的优势。卡普托博士的研究计划将通过双管齐下的方法来解决这个问题。首先是开发更环保的催化剂来制造这些所需的材料-催化剂是一种分子，它降低了化学反应的障碍，使它们能够使用更少的能量进行。不幸的是，许多工业催化剂都是基于贵金属的，这些贵金属稀有，昂贵且不可持续。卡普托博士的研究将利用地球上丰富的主族元素开发替代品。最近的发现发现这些无金属替代品在几个关键反应中几乎与贵金属替代品一样有效，包括不饱和底物的加氢。他的研究还试图了解使这些主族催化剂有效的根本原因，并利用这些数据来创建上级系统。第二种方法是从可再生原料中开发增值分子，而不是普遍使用的石油原料。该计划将对特定的天然产品应用合成化学方法，开发出第一种长效个人产品，最初针对超长效防晒。这些都有可能给个人护理领域带来革命性的变化，无疑会带来重大的知识产权保护和商业化。