Microscopy, diffraction and spectroscopy of surfactant monolayer films

表面活性剂单层膜的显微镜、衍射和光谱

• 批准号: RGPIN-2019-04036
• 负责人: Paige, Matthew
• 金额: $ 2.04万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=748039
• 关键词: Microscopy; diffraction; spectroscopy; surfactant; monolayer

The goals of this research program in surfactant films are: (1) to investigate molecular-level structure-function relationships in monolayer films comprised of a new type of anionic gemini surfactant; (2) to investigate electronic energy transfer dynamics in multifluorophoric photopolymer films using single-molecule fluorescence spectroscopy; and (3) to develop cutting-edge spectroscopy tools for molecular-level characterization of monolayers at the air-water interface.  The program will generate fundamental knowledge that will inform applied aspects of our group's research, including work on crop protection and edible oil encapsulation, as well as provide high-caliber training of HQP in areas of economic importance to Canada.   Over the program's duration, we will investigate: (1) Fundamental structure-function relationships in monolayer films comprised of a newly-discovered class of anionic gemini surfactants.  The key issue of interest is how the molecular structure of surfactants affects fundamental monolayer properties including lateral packing density, ion-binding capacity, mechanical stability and shear rheology.  Studies will involve thermodynamic, microscopic and diffraction-based structural characterization of monolayers supported by chemical synthesis to prepare custom surfactants as required. (2) Molecular-level factors that regulate electronic energy transfer efficiency in coupled, luminescent molecules in thin films.  The systems of interest are fluorescent polydiacetylene films prepared from polymerizable surfactants.  We will measure energy transfer efficiency in these films and correlate alignment of individual fluorophores in the photopolymers with energy transfer dynamics. Measurements will use single-molecule fluorescence anisotropy imaging in combination with traditional fluorescence measurements supported by quantum chemical calculations.  (3)  New spectroscopic tools for measuring molecular-level structure of films at the air-water interface, including polarization modulated infrared reflection absorption spectroscopy and sum frequency generation vibrational spectroscopy.  The former will make use of unique, high-intensity synchrotron radiation to enable unprecedented temporal resolution, and the latter will build on our expertise with pico- and femtosecond laser instrumentation.  This program will advance fundamental research in materials science, inform applied surfactant research and provide world-class training of HQP in areas of national importance.

本研究计划的主要目的是：（1）研究一种新型阴离子双子表面活性剂构成的单分子膜的分子水平的结构-功能关系：（2）利用单分子荧光光谱研究多荧光光聚合物膜中的电子能量传递动力学;以及（3）开发用于空气-水界面单层分子水平表征的尖端光谱工具。 该计划将产生基础知识，将告知我们集团的研究应用方面，包括作物保护和食用油封装的工作，以及在加拿大经济重要性领域提供高素质的HQP培训。 在项目期间，我们将调查：（1）由一类新发现的阴离子双子表面活性剂组成的单分子膜的基本结构-功能关系。我们感兴趣的关键问题是表面活性剂的分子结构如何影响单分子膜的基本性质，包括侧向堆积密度、离子结合能力、机械稳定性和剪切流变性。研究将涉及热力学、通过化学合成支持的单分子层的显微镜和基于衍射的结构表征，以根据需要制备定制的表面活性剂。(2)调节薄膜中耦合发光分子中电子能量转移效率的分子水平因素。我们感兴趣的体系是由可聚合表面活性剂制备的荧光聚二乙炔薄膜。 我们将测量这些薄膜中的能量转移效率，并将光聚合物中单个荧光团的排列与能量转移动力学相关联。测量将使用单分子荧光各向异性成像与量子化学计算支持的传统荧光测量相结合。（3）测量空气-水界面处薄膜分子水平结构的新光谱工具，包括偏振调制红外反射吸收光谱和和频产生振动光谱。前者将利用独特的，高强度同步辐射，以实现前所未有的时间分辨率，后者将建立在我们的专业知识与皮科和飞秒激光仪器。该计划将推进材料科学的基础研究，通知应用表面活性剂研究，并提供世界一流的培训HQP在国家重要领域。