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Characterization of High-Risk Atherosclerosis with Selective Positron Emission Tomography Radiotracers for Matrix Metalloproteinase-13

Characterization of High-Risk Atherosclerosis with Selective Positron Emission Tomography Radiotracers for Matrix Metalloproteinase-13
使用基质金属蛋白酶 13 的选择性正电子发射断层扫描放射性示踪剂表征高风险动脉粥样硬化
批准号：
476334
负责人：
Buchler Ariel
金额：
$7.65万
依托单位：
University of Ottawa Heart Institute
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-11-01 至 2025-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=476334&lang=en
关键词：
Atherosclerosis Autoradiography Biodistribution And Metabolism Enzyme Inhibition Extracellular Matrix Matrix Metalloproteinase Medicinal Chemistry Molecular Imaging Positron Emission Tomography Imaging Radiochemistry

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Cardiovascular disease, including heart failure and atherosclerosis, is the second leading cause of death in Canada, representing an immense public health concern. Atherosclerosis is an inflammatory disease whereby fatty deposits, known as plaques, accumu
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Selective imaging of matrix metalloproteinase-13 to quantify extracellular matrix remodelling in atherosclerosis
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