Environmental Toxicology

环境毒理学

• 批准号: CRC-2021-00131
• 负责人: Kwong, Raymond
• 金额: $ 5.46万
• 依托单位: York University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=750748
• 关键词: Environmental; Toxicology

The primary goals of Dr. Kwong's research program are to understand i) the molecular and physiological effects of environmental stressors (e.g., anthropogenic contaminants), and ii) the fundamental mechanisms regulating homeostatic processes in aquatic animals. The study will integrate molecular physiological approaches with functional genetics to investigate environment-gene-phenotype relationship and to identify the molecular pathways that underlie the effects and tolerance. This innovative strategy will facilitate the development of next-generation predictive tools that can more reliably evaluate the effects of environmental changes on aquatic animals. Ultimately, findings from the proposed research will contribute to the development of better strategies for water quality regulation and more relevant criteria for the protection of aquatic life and biodiversity.

邝博士的研究计划的主要目标是了解i）环境压力的分子和生理效应（例如，人为污染物），以及ii）调节水生动物体内平衡过程的基本机制。该研究将整合分子生理学方法和功能遗传学来研究环境-基因-表型关系，并确定影响和耐受性的分子途径。这一创新战略将促进下一代预测工具的开发，这些工具可以更可靠地评估环境变化对水生动物的影响。最终，拟议研究的结果将有助于制定更好的水质管理战略和更相关的水生生物和生物多样性保护标准。