Identification of novel dendritic cell-activating secretomes to generate anti-tumour immunity in Glioblastoma.

鉴定新型树突状细胞激活分泌组以在胶质母细胞瘤中产生抗肿瘤免疫。

• 批准号: 486042
• 负责人: Verburg Shayla G
• 金额: $ 1.27万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486042&lang=en
• 关键词: Antigen Processing And Presentation; Cold Tumor; Cytotoxic T-Cell Infiltration; Dendritic Cell Co-Culture; Dendritic Cell Vaccine; Glioblastoma Immunotherapy; Mass Spectrometry; Programmed Cell Death; Rna Sequencing; Secretome Analysis

The immune system is a powerful ally in fighting cancer. A subset of immune cells, called antigen-presenting cells, can ingest parts of the tumor, and display it to a group of white blood cells called T-cells. The T-cells that recognize the tumor fragment

免疫系统是抗击癌症的强大盟友。免疫细胞的一个子集，称为抗原提呈细胞，可以摄取肿瘤的某些部分，并将其显示给一组称为T细胞的白细胞。识别肿瘤碎片的T细胞