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Functional interactions between myogenic factors and REST/NRSF in regulation of heterochromatin during skeletal muscle regeneration

Functional interactions between myogenic factors and REST/NRSF in regulation of heterochromatin during skeletal muscle regeneration
骨骼肌再生过程中生肌因子与 REST/NRSF 之间异染色质调节的功能相互作用
批准号：
371113
负责人：
Soleimani Vahab D
金额：
$48.49万
依托单位：
CIUSSS de Centre-Ouest-de-l'Ile-de-Montral-Jewish General
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=371113&lang=en
关键词：
Chip-Seq Chromatin Epigenetics Muscle Stem Cell Rna-Seq Transcription Factors

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中文摘要
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英文摘要
Adult stem cells are the drivers of tissue repair and regeneration. In skeletal muscle a rare population of Muscle Stem Cells, also called the Satellite Cells reside within muscle tissue in an undifferentiated state, poised to enter myogenic program upon
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Targeting Age-Activated Proinflammatory Chemokine Signaling by CCL2/11 to Enhance Skeletal Muscle Regeneration in Aging
Molecular Regulation of Muscle Stem Cell Homeostasis
Canada Research Chair Tier 2
  • 批准号：
    315509
  • 项目类别：
  • 资助金额：
    $36.43万
  • 财政年份：
    2014
  • 负责人：
    Soleimani Vahab D
  • 依托单位：
    McGill University
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