New functions for bioactive flavonoids in plants and mammals

植物和哺乳动物中生物活性黄酮类化合物的新功能

• 批准号: DP1096299
• 负责人: Em/Prof Michael Djordjevic
• 金额: $ 27.16万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-02-04 至 2013-02-03
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1096299
• 关键词: New; functions; bioactive; flavonoids; plants

We have discovered natural products with biological activity in plants and mammals. These molecules affect plant shape and development and the process of mammalian blood vessel formation. We seek to understand how these molecules work. More understanding is required before one can begin to utilise these molecules for possible beneficial agriculture or human health outcomes. Plant shape influences such things as yield or more drought-resilient root systems. Importantly, we have discovered specific molecules that either promote or inhibit blood vessel formation. A better understanding of how these molecules work could lead to novel treatments for cancer or cardiovascular disease.

我们在植物和哺乳动物中发现了具有生物活性的天然产物。这些分子影响植物的形状和发育以及哺乳动物血管形成的过程。我们寻求了解这些分子如何工作。在人们开始利用这些分子用于可能有益的农业或人类健康结果之前，需要更多的了解。植物的形状会影响产量或更耐旱的根系。 重要的是，我们已经发现了促进或抑制血管形成的特定分子。 更好地了解这些分子如何工作可能会导致癌症或心血管疾病的新疗法。