Role of epigenetic modulation in breast cancer etiology and drug resistance.
Role of epigenetic modulation in breast cancer etiology and drug resistance.
批准号:
368101
负责人:
Muller William J
金额:
$43.71万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-08-01 至 2020-08-01
中文摘要
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英文摘要
Inactivation of tumor suppressors is associated with poor outcome in breast cancer, yet the underlying mechanisms are poorly understood. One underlying mechanism of gene repression is though modification of histones that influence chromatin structure. In
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Development of a pre-clinical mouse model of Estrogen receptor alpha positive breast cancer to investigate the clinical efficacy of Selective Estrogen Receptor Modulators (SERMs)
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批准号:341360
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Oncogene-mediated signal transduction in ErbB2 transgenic models of mammary tumour progression
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依托单位:
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The role of Epidermal Growth Factor Receptor Family in mammary tumorigenesis and metastasis
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国内基金
海外基金
高等植物远缘杂交诱导的表观遗传变异(epigenetic variation)现象及其在物种进化和新种形成中的作用
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批准号:30430060
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批准年份:2004
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负责人:刘宝
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依托单位: