Role of epigenetic modulation in breast cancer etiology and drug resistance
Role of epigenetic modulation in breast cancer etiology and drug resistance
批准号:
277365
负责人:
Muller William J
金额:
$54.64万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-12-01 至 2017-12-01
中文摘要
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英文摘要
The major objective of this proposal is to evaluate the contribution of a gene known as EZH2 in breast cancer progression. Using a number of well-defined mouse models we will assess whether elevated expression of EZH2 in breast cancer cells confers resist
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Chi3L1 (YKL-40) plays a multifaceted role in modulating tumor immune microenvironment during breast cancer progression.
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依托单位:
Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.
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批准号:483129
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Identification of Stat1 signaling pathway(s) involved in mediating tumor escape from immune surveillance.
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财政年份:2023
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The multifaceted role of c-Src tyrosine kinase in breast cancer progression.
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批准号:468470
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资助金额:$83.6万
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财政年份:2022
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依托单位:
Chi3L1 (YKL-40) plays a multifaceted role in modulating tumor immune microenvironment during breast cancer progression.
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批准号:472379
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资助金额:$7.29万
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财政年份:2022
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负责人:Muller William J
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依托单位:
Role of epigenetic modulation in breast cancer etiology and drug resistance.
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批准号:368101
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财政年份:2017
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依托单位:
The role of an alternative ErbB2 splice isoform in lung and breast cancer progression.
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批准号:341907
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依托单位:
Oncogene-mediated signal transduction in transgenic mouse models of human breast cancer
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批准号:333085
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依托单位:
Canada Research Chair Tier 1
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批准号:341360
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项目类别:
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资助金额:$101.99万
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财政年份:2015
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依托单位:
Oncogene-mediated signal transduction in ErbB2 transgenic models of mammary tumour progression
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批准号:280158
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资助金额:$56.09万
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财政年份:2013
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依托单位:
Identification of PI-3K coupled signalling pathways involved in mammary tumour progression: Implication for resistance to targeted therapy.
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批准号:291796
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财政年份:2013
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依托单位:
Integrin-mediated signal transduction in mammary tumourigenesis and metastasis
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批准号:249551
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资助金额:$7.29万
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财政年份:2011
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负责人:Muller William J
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依托单位:
The role of ErbB2-14-3-3 sigma signaling axis in cancer and development
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批准号:199253
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财政年份:2010
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依托单位:
The role of Epidermal Growth Factor Receptor Family in mammary tumorigenesis and metastasis
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批准号:171470
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依托单位:
国内基金
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依托单位: