How triadin and junctin communicate with ryanodine receptors deep within a calcium store to determine skeletal muscle contraction

三联蛋白和连接蛋白如何与钙库深处的兰尼碱受体通讯以确定骨骼肌收缩

• 批准号: DP1094219
• 负责人: Prof Angela Dulhunty
• 金额: $ 21.58万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1094219
• 关键词: How; triadin; junctin; communicate; ryanodine

The project results will provide a platform for muscle relaxants and other drugs that will specifically target either the heart or skeletal muscle and will have applications in the livestock, veterinary and pharmaceutical Industries. The project falls within the National Research Priorities of Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries, as well as the national priority goal of Ageing well, Ageing Productively. The project will be of national benefit in training undergraduate students, PhD students and a postdoctoral fellow in state-of-the-art techniques in an internationally competitive research field.

该项目的结果将为肌肉松弛剂和其他药物提供一个平台，这些药物将专门针对心脏或骨骼肌，并将在畜牧业，兽医和制药行业中应用。该项目福尔斯促进和保持良好健康的国家研究重点和建设和改造澳大利亚工业的前沿技术，以及老龄化的国家优先目标。该项目将在培养本科生，博士生和博士后研究员在国际竞争力的研究领域的最先进的技术国家的利益。