INTRINSIC PROPERTIES OF THE PORE FORMING DOMAIN OF THE RYANODINE RECEPTOR CALCIUM CHANNEL

兰尼碱受体钙通道成孔结构域的固有特性

• 批准号: DP0557780
• 负责人: Prof Angela Dulhunty
• 金额: $ 24.93万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0557780
• 关键词: INTRINSIC; PROPERTIES; PORE; FORMING; DOMAIN

The project is to understand how a calcium ion channel is able to regulate muscle performance. The ion channel, known as the ryanodine receptor, is essential for human and animal survival. The results of the project will be integral to understanding muscle performance in humans and will have long term implications for Australian sports physiology and sports science. The project will also be integral to understanding muscle performance and development in animals and will have repercussions for the Australian livestock and racing industries. The results may lead to the development of new insecticides since insect mobility depends on ryanodine receptor activity. This will benefit to Australian agriculture.

该项目旨在了解钙离子通道如何能够调节肌肉性能。 这种离子通道被称为ryanodine受体，对人类和动物的生存至关重要。 该项目的结果将是理解人类肌肉性能不可或缺的，并将对澳大利亚运动生理学和运动科学产生长期影响。 该项目也将是了解动物肌肉表现和发育的不可或缺的一部分，并将对澳大利亚畜牧业和赛马业产生影响。这一结果可能会导致开发新的杀虫剂，因为昆虫的流动性取决于兰尼碱受体的活性。 这将有利于澳大利亚农业。