INTRINSIC PROPERTIES OF THE PORE FORMING DOMAIN OF THE RYANODINE RECEPTOR CALCIUM CHANNEL

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The project is to understand how a calcium ion channel is able to regulate muscle performance. The ion channel, known as the ryanodine receptor, is essential for human and animal survival. The results of the project will be integral to understanding muscle performance in humans and will have long term implications for Australian sports physiology and sports science. The project will also be integral to understanding muscle performance and development in animals and will have repercussions for the Australian livestock and racing industries. The results may lead to the development of new insecticides since insect mobility depends on ryanodine receptor activity. This will benefit to Australian agriculture.