铜催化作为有机合成化学研究的重要领域，近来取得了很大的进展。然而大部分铜催化有机合成研究仍仅关注于有机合成方法学的探索，基于配体设计及相应的铜配合物为出发点的有机合成研究却关注的较少。双官能团策略的配体设计及相应金属配合物导向的合成方法学近来取得了极大进展。在双官能团配体的“协同作用”下，金属配合物可以完成单一官能团配体难以实现的有机化学转换。该策略已成功应用于过渡金属如金、银、钯等，而基于双官能团配体支撑的铜配合物的化学转化只有较少报道。因此，基于双官能团配体支撑的铜配合物的合成及相应催化性质研究是一个很好的研究课题。本课题中，我们拟设计若干含有双官能团的有机配体。在该类双官能团有机配体中，一方面通过引入有机膦或NHC等软配体来络合稳定铜金属中心，另一方面通过配体内另一官能团来调控有机反应中底物的反应活性。在此基础上合成若干双官能团配体支撑的铜配合物，并对其在催化活性开展系统性的研究。

Homogeneous copper catalysis has experienced exponential development over the past decade. However, literature survey reveals that reports of homogeneous copper catalysis based on ligand design and corresponding organometallic complex synthesis is rare. Recently much progress has been made in the field of synthesis methodology starting from bifunctional ligand design. By utilizing these bifunctional ligand, organometallic complex could realize some unique chemical transformation. However, little attention have been paid in the field of homogeneous copper catalysis based on bifunctional ligand design. In this study, we aim to design a series of bifunctional ligands including phosphine ligands or NHC ligands as well as the other functional group. In these ligands, we use the phosphine ligands or NHC ligands to support the copper metal core, and control the reaction property with the help of the other functional group. With these bifunctional ligands, we attempt to synthesize the corresponding bifunctional copper complexes, and thus develops new synthetic methodologies for the construction of new chemical bonds and chemical skeletons.