现今社会，半导体已经成为了现代电子和光学工业中不可或缺的核心部分，而目前已有的半导体材料在一些领域，特别是在例如生物系统交互领域和原子制造之类的新兴领域存在一定的固有缺陷，所以发展新型的可调谐生物相容半导体仍是巨大的挑战。自组装多肽晶体体系以其简单的制备方法，高效的组装方式，优秀的生物相容性和环境友好性等特点成为仿生耐久半导体的理想材料。本项目针对目前自组装多肽晶体半导体种类较少，缺乏有效的组装结构与力学和半导体性质对应关系理论，难以实现多肽半导体器件与生物体系接驳等问题，将通过对自组装多肽晶体的组装结构分析，提出组装结构中亲水部，疏水部，氢键以及芳香环堆积排列方式与力学半导体性质的对应关系理论，设计和制备新型的自组装多肽晶体半导体材料，并且尝试进行实际的多肽半导体器件设计和应用，在建立自组装多肽半导体设计原则，延伸自组装多肽材料的应用领域，实现仿生材料与生物体系结合等方面具备重要的意义。

Nowadays, semiconductors have been the key point to the modern electronics and optics industries. Traditional semiconductors bear some limitations in emerging fields such as interfacing with biological systems and bottom-up fabrication. The self-assembly peptide crystal systems are ideal candidates for the bioinspired and durable nanoscale semiconductors due to the simple preparation methods, high effective assembly, outstanding biocompatibility and environmental friendliness. This project will focus on the points including extending the range of self-assembly peptide crystal semiconductors, building the correspondence theory between the nanostructure and physicl properties as well as interfacing with biological systems. By analyzing the crystal structures and study the physical properties of the existed self-assembly peptide crystals, we would like to propose the theory about the correspondence between nanostructure and physicl properties of crystals and design the new kinds of semiconductors based on the self-assembly peptide crystals. Furthermore, we also plan to design semiconductor device and accomplish the interfacing with biological systems with the self-assembly peptide crystals. This work will build the design principles of self-assembly peptide crystal, extend the application domains of self-assembly peptides and demonstrate the possibility of connecting peptide semiconductor with living systems in principle.