拓扑化智能型树枝化聚合物

新型拓扑结构聚合物的有效合成，并赋予其智能响应性，将进一步丰富聚合物结构种类，加深理解聚合物结构与性能的关系，同时拓展复杂结构聚合物在智能材料领域的应用价值。本课题拟采用我们团队近年来成功开拓的烷氧醚类树枝化聚合物为结构基元，经共价、超分子或动态键联方式构筑刷形、星形和环形拓扑结构的新型树枝化聚合物，集烷氧醚树枝化聚合物优异的生物相容性及卓越的温敏特性于一体，重点研究这类纳米尺度智能单分子的拓扑结构形成过程，探索拓扑结构与智能响应性之关系，深入研究它们受温度诱导的聚集过程及聚集体形貌。探讨此类大尺度拓扑聚合物在结构转换或温敏诱导聚集过程中对客体小分子的控制与迁移作用，进而研究其在离子富集与识别、荧光传感及药物控释等领域的基础应用。该项目的成功实施，不仅将提供合成和表征新型复杂结构智能聚合物的有效方法，同时为拓展智能树枝化聚合物的材料应用奠定基础。

Topology of polymers plays a key role in controlling their self-assembly and morphologies in bulk or in solutions, therefore, their efficient synthesis has received considerable attention recently to develop polymers of novel topological structures, and to enhance the understanding of structural effects on polymer properties. We propose in this project to combine the advantages from thermoresponsive oligo(ethylene glycol)-based dendronized polymers with topological polymer architectures, and to synthesize brush-like, star-like and circular dendronized polymers. They are proposed to be prepared through covalent and dynamic covalent linkages, or through supramolecular interactions. These polymers are designed on the purpose to compare the topological effects on their thermoresponsive properties, as well as thermally-induced aggregation and morphologies of the aggregates. The synthetic routes will be compared with regards to the structure regularity and synthesis efficiency. This proposed project will also focus on the characteristic properties of dendronized polymers in hosting the guest molecules, and topological effects on controlling the transitions of the guest molecules during the thermally-induced phase transition processes. It is hoped that the success of this planned research project will eventually lead to better understanding of topological effects on polymer properties, and pave a way for developing novel stimuli-responsive dendronized polymer materials.