利用国外照明及医学领域最新研究成果，针对大型流水线工厂作业光环境的光生物安全隐患，运用先进的视光学、心理学及电生理测试手段，研究轮班工人疲劳周期，建立精细视觉作业工人疲劳数据集和模拟模型；通过工作- - 休息优化排程，研究在人眼视觉与非视觉效应双重作用下，以低能量照明提升工作效率的可能性，降低人工光高剂量长期累积引发的健康风险；利用短波光作为生物钟重设定的刺激条件，对用于增强轮班适应性的夜间明亮/黑暗策略进行安全性验证，提出人工光安全曝光量预测公式；对不同照明模式边界阈值下人体反应进行量化研究，建立具有昼夜适应性、与人体节律吻合度高的工厂最佳动态人工光环境模式。 上述研究有利于消除工人疲劳累积、缓解压力，可降低长期从事轮班工作工人未来的健康风险，为职业防护标准的修订提供参考；有利于节能，为工厂照明设计标准修订提供参考。本课题为国际前沿课题，其成果有利于健康、节能，有着巨大的社会和经济效益。

Making use of the latest world research results in the area of lighting and medicine, aiming at the potential risk of photobiological safety in the lighting environment of large-scale assembly line factory works, utilizing advanced optometry, psychology and electrophysiological testing tools, we study shift workers fatigue cycle and consequently create fatigue data and simulation models of fine visual task workers. Via optimizing work-rest scheduling, we research the possibility of enhancing the work efficiency in low energy lighting in the dual role of the human visual and non-visual effects to reduce health risks which are caused by artificial long-term and high-dose light cumulation. Taking advantage of short-wave light as the biological clock to re-set the stimulation conditions, we make security authentication, which is used to strengthen adaptability of bright / dark night shifts strategy and propose prediction formula of artificial light safe exposure level. We study the human reaction the in the boundary threshold of different lighting modes and consequently establish best dynamic factory artificial light environment mode which has circadian adaptability and high consistency with human rhythm. The above research is helpful to eliminate the workers' fatigue cumulation, relieve pressure and reduce workers future health risks that are long engaged in shift work and therefore can provide reference for occupational protection standard revision. At the same time, it is useful to energy conservation and provides reference for the standard revision for factory lighting design. This topic is an international front topic,whose result is good for health keeping, energy saving and may bring to huge social and economic benefits.