配位作用驱动的分子容器的设计、合成及性质研究是目前国际化学界研究的前沿和热点问题之一。本研究计划是通过调控有机配体的尺寸和结构（杂环桥联和开链冠醚桥联的有机配体）以及无机离子配位喜好的选择定向设计合成新型的具有预想空穴或内腔的配位作用驱动的金属－有机分子容器，进而通过有机模板与平衡阴离子协同作用来调谐和实现对特定客体组份（有机异构体和几何形状相似的阴离子物种）等进行选择性识别和分离，继而研究其谱学信号，尤其是光信号的实时变化，寻找对某类客体组份（如与人类生活、环境保护和工农业生产息息相关的物种）的有效和实用的传感器。. 不仅如此，我们还将对新的金属－有机主客组装体的识别和分离的机理进行初步探讨，并对其作为色谱填充材料（固定相）的应用研究做出初步尝试。该研究将为基于配位作用驱动的金属-有机容器的识别分离和传感提供新的方法和途径。

Coordination-driven metal-organic molecular containers are a very attractive and interesting class of porous materials due to their applications for gas storage and organic molecule separation, catalysis, luminescent and magnetic properties.This research project will focus on design and synthesis of coordination-driven molecular containers based on heterocycle or acyclic crown ether bridging organic ligands and metal ions.More importantly, we will explore how the synergy of organic template and anionic species affects inside cavity space and interior microenvironment, furthermore, the properties of recognising, sensing and separating properties for specific guest substrates (including organic and anionic species).Such study will provide an alternative approach for the design and preparation of practical sensors and separators based on coordination-driven molecular containers.