在前期已经确认光呼吸途径中的关键酶−乙醇酸氧化酶 (glycolate oxidase, GOX) 与大麦条纹花叶病毒 (BSMV) γb蛋白相互作用的基础上, 着重分析BSMV侵染对GOX表达和寄主光呼吸作用的影响, 分析GOX与γb相互作用在BSMV侵染、复制和运动以及症状形成过程中对γb生物学功能的具体影响以及可能涉及的寄主途径；通过解析GOX-γb复合物的晶体结构，明确GOX与γb相互识别的结构基础，确定影响二者互作的关键氨基酸。明确本生烟GOX与γb相互作用的生物学意义及其结构基础，将为深入分析γb蛋白的多功能性、以及理解病毒−寄主植物的相互作用提供新的科学证据。

Our previous data have confirmed the interaction between Barley stripe mosaic virus (BSMV) γb and glycolate oxidase (GOX), a protein that plays a crucial role in the photorespiration pathway. Based upon this, the effect of BSMV infection on the expression of GOX and photorespiration pathway will be analyzed, and how the GOX-γb interaction affect the function of γb will be investigated, thus illustrating the roles of GOX-γb interaction played in the replication, movement and symptom development of BSMV infection as well as the host pathways involved in the impact of GOX on the γb function. In order to understand the structural basis for molecular recognition between GOX and γb, crystal structure of the GOX-γb complex will be determined. Furthermore, the key amino acid residues those are essential for GOX-γb interaction will be localized. These results would reveal the functional roles of GOX-γb interaction as well as its biological significance, thereby facilitating understanding of the multifunctional γb protein and providing new insights into the molecular mechanisms underlying virus-host interaction.