植物天然防腐成分因其低毒、低残留、对环境影响小而逐渐成为木竹材防腐研究的热点。项目组前期研究发现黄芩素等类黄酮化合物对木竹材具有防霉防腐特效，然而黄芩素等类黄酮化合物在木竹材中固着性较差, 使其在自然环境中的防腐效果不能持久，致使不能被木竹材改性行业广泛应用，制约着木竹材天然防护技术发展。.因此，本项目拟以黄芩素等类黄酮化合物为研究对象，解析其油溶性基团和金属盐取代基的结构修饰途径，初步确定黄芩素等类黄酮化合物的结构修饰次序，通过在黄芩素等类黄酮化合物基础上引入油溶性基团和金属盐取代基进行结构修饰叠加与耦合，以加强其稳定性、固着性和抗流失，设计并合成具有疏水性能好、固着性强、抗流失性能优的木材防腐剂，最终揭示黄芩素等类黄酮化合物结构修饰与抑菌增效机理。这一研究将在我国人工林木材天然防护技术领域中实现重大理论突破。

Anticorrosion agents from plants have been becoming a hot research topic of bamboo wood preservatives due to their low toxicity and residue. We have recently revealed that flavonoids such as baicalein showed excellent anticorrosion against bamboo wood. However, flavonoids are prone to loss in natural conditions, and are not widely used in wood and bamboo modification. Development of protection technology for bamboo with natural flavonoids is therefore restricted..In the present project, flavonoids such as baicalein are used as leads, and structural modification with oleoyl chloride and metal-salt will be explored. Modificantion steps will be sorted and the structural synergism and coupling will be researched for modify their anti-corrosion, permeability and bondability, which aims to disclose the synergistic mechanism of anti-micromism. This research will lead to a key theoretical breakthrough in field of anticorrosive agents with high potency and low toxicity.