近年来，荧光生物成像技术已经发展成为生理过程观测和疾病早期诊断治疗的重要方法之一。而荧光聚合物纳米成像材料由于其易于实现的制备方法、出色的光学性能、大的比表面积和良好的生物相容性等优点，已经成为一种非常重要的荧光成像材料。本项目针对既具有高效近红外（红光）发光性能且不存在染料泄漏的量子点成像材料仍有待进一步开发的现状，荧光纳米成像材料的特异性识别及拓展其功能性上仍有待进一步提高等问题，拟开发具有AIE特性、高效红光-近红外发射、生物相容性良好、功能性或特异性出色和具有自主知识产权的荧光共聚物量子点，进一步提升荧光成像的准确性和质量，为生理和病理过程观测、肿瘤疾病的早期诊断及治疗提供材料基础和理论依据。

Fluorescence imaging technology is an important method for physiological process observation and early diagnosis and treatment of disease. Fluorescence imaging polymer nano materials has become very important in bioimaging, because of easy preparation method, excellent optical performance, large specific surface area and good biocompatibility. However, the AIE fluorescent nano bioimaging materials with both near-infrared (red) light and no dye leak are quite limited. Moreover, the functional or strong targeting capabilities of fluorescence imaging materials remain to be further improved. This project aims to fabricate novel fluorescence imaging materials with independent intellectual property rights, which possess AIE characteristics, excellent luminous performance, good biocompatibility and stability and outstanding functional or strong targeting ability. It is to further enhance the accuracy and quality of the fluorescence imaging, to provide new effective material basis and theoretical basis for observing of pathological process or early diagnose and management of tumor diseases.