水稻穗发育与产量和品质密切相关，其发育过程涉及顶端分生组成活性、侧生器官发育及其特性的维持等复杂的生物学基本问题。近年来已成功克隆了多个控制水稻穗发育的重要基因，但是其遗传调控网络尚不清楚。本项目拟在前期克隆控制水稻株型、穗型及产量性状进化基因PROG1和OsLG1的基础上，通过EMS诱变携带PROG1或OsLG1基因的野生稻渗入系，筛选穗发育相关突变体，利用正向遗传学方法，分离控制穗发育及产量性状的新基因，分析其与PROG1、OsLG1及其他产量性状基因的遗传互作关系，揭示其参与的遗传调控网络，并探索这些基因的生产应用潜力。本项目研究结果不仅为解析水稻穗发育及产量性状遗传调控网络这一重要科学问题提供参考，而且将为水稻产量性状的分子改良提供新的基因。

Panicle development is associated with grain yield and quality in rice which involves complex biological processes, including shoot apical meristem activity, lateral organ development, and maintenance of characteristics. Some important genes controlling panicle development have recently been identified in rice, however, their regulatory networks still remain unknown. Our group has previously cloned two key genes, PROG1 and OsLG1, regulating the domestication of plant architecture, panicle architecture and yield-related traits in rice. The aim of the proposed study is (1) to induce introgression lines harboring PROG1 or OsLG1 by EMS treatment and select mutants in panicle development; (2) to isolate genes related to panicle development and yield using forward genetics approach; and (3) analyze its relationship with PROG1, OsLG1 and other yield related genes, reveal the genetic regulatory network of these genes, and explore their potential application. The results of the study will not only shed light on the regulatory network of rice panicle development, but also provide novel genes for rice improvement.