Interoception in anxiety and depression.
Interoception in anxiety and depression.
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DOI:
10.1007/s00429-010-0258-9
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发表时间:
2010-06
影响因子:
3.1
通讯作者:
Stein, Murray B.
中科院分区:
文献类型:
--
作者:
Paulus, Martin P.;Stein, Murray B.
We review the literature on interoception as it relates to depression and anxiety, with a focus on belief, and alliesthesia. The connection between increased but noisy afferent interoceptive input, self-referential and belief-based states, and top-down modulation of poorly predictive signals is integrated into a neuroanatomical and processing model for depression and anxiety. The advantage of this conceptualization is the ability to specifically examine the interface between basic interoception, self-referential belief-based states, and enhanced top-down modulation to attenuate poor predictability. We conclude that depression and anxiety are not simply interoceptive disorders but are altered interoceptive states as a consequence of noisily amplified self-referential interoceptive predictive belief states.
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