Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis.
Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis.
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DOI：
10.1371/journal.pone.0015564
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发表时间：
2011-01-26
期刊：
影响因子：
3.7
通讯作者：
HALCyon study team
中科院分区：
文献类型：
--
作者：
Birnie K;Cooper R;Martin RM;Kuh D;Sayer AA;Alvarado BE;Bayer A;Christensen K;Cho SI;Cooper C;Corley J;Craig L;Deary IJ;Demakakos P;Ebrahim S;Gallacher J;Gow AJ;Gunnell D;Haas S;Hemmingsson T;Inskip H;Jang SN;Noronha K;Osler M;Palloni A;Rasmussen F;Santos-Eggimann B;Spagnoli J;Starr J;Steptoe A;Syddall H;Tynelius P;Weir D;Whalley LJ;Zunzunegui MV;Ben-Shlomo Y;Hardy R;HALCyon study team
握力、步行速度、站起来和站立平衡时间是衡量身体能力的客观指标，可以表征老年人当前的健康状况，并预测老年人的生存。儿童时期的社会经济地位（SEP）可能会影响成年早期身体能力的峰值水平，从而影响成年后期的水平。我们通过荟萃分析进行了一项系统综述，以验证儿童时期不良SEP与成年后客观测量的身体能力水平较低相关的假设。2010年5月之前发表的相关研究通过EMBASE和MEDLINE进行文献检索。未发表的结果来自研究人员。所有研究人员以标准格式提供结果，并使用随机效应荟萃分析进行汇总。本综述纳入了19项研究。meta分析的总样本量范围从椅子上升时间N = 17,215到握力N = 1,061,855。虽然发现了异质性，但在年龄调整模型中有一致的证据表明，较低的儿童SEP与成年后身体能力水平的适度下降有关：与最低和最高的儿童SEP相比，握力减少了0.13个标准差(95% CI：0.06, 0.21)，平均步行速度降低0.07米/秒（0.05,0.10），平均站起来时间增加6%(4%,8%)，无法平衡5秒的比值比为1.26（1.02,1.55）。调整潜在的中介因素，成人SEP和体型大大减弱了相关性。然而，尽管这种衰减，对于步行速度和椅子起身时间，仍然有证据表明存在适度的关联。针对儿童时期社会经济不平等的政策可能在促进在以后生活中保持独立方面有额外的好处。
Grip strength, walking speed, chair rising and standing balance time are objective measures of physical capability that characterise current health and predict survival in older populations. Socioeconomic position (SEP) in childhood may influence the peak level of physical capability achieved in early adulthood, thereby affecting levels in later adulthood. We have undertaken a systematic review with meta-analyses to test the hypothesis that adverse childhood SEP is associated with lower levels of objectively measured physical capability in adulthood. Relevant studies published by May 2010 were identified through literature searches using EMBASE and MEDLINE. Unpublished results were obtained from study investigators. Results were provided by all study investigators in a standard format and pooled using random-effects meta-analyses. 19 studies were included in the review. Total sample sizes in meta-analyses ranged from N = 17,215 for chair rise time to N = 1,061,855 for grip strength. Although heterogeneity was detected, there was consistent evidence in age adjusted models that lower childhood SEP was associated with modest reductions in physical capability levels in adulthood: comparing the lowest with the highest childhood SEP there was a reduction in grip strength of 0.13 standard deviations (95% CI: 0.06, 0.21), a reduction in mean walking speed of 0.07 m/s (0.05, 0.10), an increase in mean chair rise time of 6% (4%, 8%) and an odds ratio of an inability to balance for 5s of 1.26 (1.02, 1.55). Adjustment for the potential mediating factors, adult SEP and body size attenuated associations greatly. However, despite this attenuation, for walking speed and chair rise time, there was still evidence of moderate associations. Policies targeting socioeconomic inequalities in childhood may have additional benefits in promoting the maintenance of independence in later life.
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影响因子：
4.1
作者：
Deary IJ;Gow AJ;Taylor MD;Corley J;Brett C;Wilson V;Campbell H;Whalley LJ;Visscher PM;Porteous DJ;Starr JM
通讯作者：
Starr JM
影响因子：
4.1
作者：
Cesari M;Onder G;Zamboni V;Manini T;Shorr RI;Russo A;Bernabei R;Pahor M;Landi F
通讯作者：
Landi F
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N
DOI：
10.1093/gerona/glp078
发表时间：
2009-10-01
影响因子：
5.1
作者：
Brunner, Eric;Shipley, Martin;Marmot, Michael
通讯作者：
Marmot, Michael
影响因子：
5.7
作者：
Buchman, Aron S.;Wilson, Robert S.;Bennett, David A.
通讯作者：
Bennett, David A.