Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments.
Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments.
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DOI：
10.1088/2040-8986/aab3a6
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发表时间：
2018-04
期刊：
影响因子：
--
通讯作者：
Tachtsidis I
中科院分区：
文献类型：
--
作者：
Giannoni L;Lange F;Tachtsidis I
高光谱成像（HSI）技术已被广泛用于医学研究，针对各种生物现象和多种组织类型。它们在宽波长范围内的高光谱分辨率使得能够获取对应于不同光相互作用生物化合物的空间信息。本文就HSI在生命科学中监测脑组织代谢和血流动力学的应用作一综述。已经研究了涉及HSI的不同方法来评估和量化脑活动，主要集中在：（1）通过测量氧合（HbO 2）和脱氧（HHb）血红蛋白的变化来绘制组织氧输送图;以及（2）评估脑氧代谢率（CMRO 2）以估计脑组织的氧消耗。最后，我们介绍了大脑代谢HSI的未来前景，包括其对直接参与细胞能量产生的分子的光学信号成像的潜在用途。HSI解决方案可以为了解脑组织代谢和氧合提供显着的见解，有助于研究脑组织生理过程。
Hyperspectral imaging (HSI) technologies have been used extensively in medical research, targeting various biological phenomena and multiple tissue types. Their high spectral resolution over a wide range of wavelengths enables acquisition of spatial information corresponding to different light-interacting biological compounds. This review focuses on the application of HSI to monitor brain tissue metabolism and hemodynamics in life sciences. Different approaches involving HSI have been investigated to assess and quantify cerebral activity, mainly focusing on: (1) mapping tissue oxygen delivery through measurement of changes in oxygenated (HbO2) and deoxygenated (HHb) hemoglobin; and (2) the assessment of the cerebral metabolic rate of oxygen (CMRO2) to estimate oxygen consumption by brain tissue. Finally, we introduce future perspectives of HSI of brain metabolism, including its potential use for imaging optical signals from molecules directly involved in cellular energy production. HSI solutions can provide remarkable insight in understanding cerebral tissue metabolism and oxygenation, aiding investigation on brain tissue physiological processes.
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影响因子：
5.7
作者：
Bainbridge A;Tachtsidis I;Faulkner SD;Price D;Zhu T;Baer E;Broad KD;Thomas DL;Cady EB;Robertson NJ;Golay X
通讯作者：
Golay X
DOI：
10.1097/00004647-199701000-00009
发表时间：
1997-01-01
影响因子：
6.3
作者：
Buxton, RB;Frank, LR
通讯作者：
Frank, LR
DOI：
10.1124/jpet.112.192138
发表时间：
2012-09-01
影响因子：
3.5
作者：
Johri, Ashu;Beal, M. Flint
通讯作者：
Beal, M. Flint
影响因子：
5.3
作者：
Brigadoi S;Phan P;Highton D;Powell S;Cooper RJ;Hebden J;Smith M;Tachtsidis I;Elwell CE;Gibson AP
通讯作者：
Gibson AP
影响因子：
3.5
作者：
ARRIDGE, SR;COPE, M;DELPY, DT
通讯作者：
DELPY, DT