Highly pathogenic avian influenza virus among wild birds in Mongolia.
Highly pathogenic avian influenza virus among wild birds in Mongolia.
复制标题
DOI：
10.1371/journal.pone.0044097
复制
发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Joly DO
中科院分区：
文献类型：
--
作者：
Gilbert M;Jambal L;Karesh WB;Fine A;Shiilegdamba E;Dulam P;Sodnomdarjaa R;Ganzorig K;Batchuluun D;Tseveenmyadag N;Bolortuya P;Cardona CJ;Leung CY;Peiris JS;Spackman E;Swayne DE;Joly DO
蒙古几乎没有家禽，但有大量的迁徙水鸟，为研究纯野生鸟类系统中高致病性禽流感病毒（HPAIV）的流行病学创造了理想的场所。在此，我们介绍 2005 年至 2011 年蒙古 HPAIV 亚型 H5N1 的主动和被动监测结果，以及五次疫情调查的结果。在此期间，蒙古总共确认了八起高致病性禽流感病毒疫情。其中，1 例是在本项目主动监测中发现的，3 例是蒙古政府机构主动监测发现的，4 例是被动监测发现的。在邻近的俄罗斯图瓦共和国的一个将国际边界一分为二的湖上，又爆发了三起疫情。从 7,855 份环境粪便样本（主要来自鸭子）或主动监测过程中捕获的 2,765 只临床健康活禽（主要是鸭、鹅和天鹅）中未分离（培养）出 HPAIV，而从主动监测中发现的 141 只临床患病或死亡的禽类中分离出 4 种 HPAIV。在主动监测过程中，从患病或死亡的禽类中培养出两种低致病性禽流感病毒（LPAIV），而环境粪便和活的健康禽类分别产生了 56 种和 1 种 LPAIV。所有蒙古暴发都发生在 2005 年和 2006 年（分支 2.2），或 2009 年和 2010 年（分支 2.3.2.1）；中国西藏和/或青海省报告春季高致病性禽流感病毒爆发的所有年份。家禽匮乏地区爆发的疫情有力地证明，野生鸟类至少可以在中等距离内携带高致病性禽流感病毒。然而，2006 年 6 月后未能检测到进化枝 2.2 的进一步爆发，以及 2010 年 6 月后未能检测到进化枝 2.3.2.1 的进一步爆发，表明进出蒙古的野生鸟类可能不具备作为 HPAIV 无限期储存宿主的能力，或者在我们的研究期间 HPAIV 并未到达易感人群。
Mongolia combines a near absence of domestic poultry, with an abundance of migratory waterbirds, to create an ideal location to study the epidemiology of highly pathogenic avian influenza virus (HPAIV) in a purely wild bird system. Here we present the findings of active and passive surveillance for HPAIV subtype H5N1 in Mongolia from 2005–2011, together with the results of five outbreak investigations. In total eight HPAIV outbreaks were confirmed in Mongolia during this period. Of these, one was detected during active surveillance employed by this project, three by active surveillance performed by Mongolian government agencies, and four through passive surveillance. A further three outbreaks were recorded in the neighbouring Tyva Republic of Russia on a lake that bisects the international border. No HPAIV was isolated (cultured) from 7,855 environmental fecal samples (primarily from ducks), or from 2,765 live, clinically healthy birds captured during active surveillance (primarily shelducks, geese and swans), while four HPAIVs were isolated from 141 clinically ill or dead birds located through active surveillance. Two low pathogenic avian influenza viruses (LPAIV) were cultured from ill or dead birds during active surveillance, while environmental feces and live healthy birds yielded 56 and 1 LPAIV respectively. All Mongolian outbreaks occurred in 2005 and 2006 (clade 2.2), or 2009 and 2010 (clade 2.3.2.1); all years in which spring HPAIV outbreaks were reported in Tibet and/or Qinghai provinces in China. The occurrence of outbreaks in areas deficient in domestic poultry is strong evidence that wild birds can carry HPAIV over at least moderate distances. However, failure to detect further outbreaks of clade 2.2 after June 2006, and clade 2.3.2.1 after June 2010 suggests that wild birds migrating to and from Mongolia may not be competent as indefinite reservoirs of HPAIV, or that HPAIV did not reach susceptible populations during our study.
登录
查看更多内容
影响因子：
11.8
作者：
Brown JD;Stallknecht DE;Beck JR;Suarez DL;Swayne DE
通讯作者：
Swayne DE
野鸭作为高度致病的鸟类流感病毒（H5N1）的长距离载体。
影响因子：
11.8
作者：
Keawcharoen, Julthatip;van Riel, Debby;van Amerongen, Geert;Bestebroer, Theo;Beyer, Walter E.;van Lavieren, Rob;Osterhaus, Albert D. M. E.;Fouchier, Ron A. M.;Kuiken, Thijs
通讯作者：
Kuiken, Thijs
影响因子：
1.3
作者：
Lee, Dong-Hun;Park, Jae-Keun;Song, Chang-Seon
通讯作者：
Song, Chang-Seon
青海湖斑头雁繁殖期和繁殖后的运动模式
影响因子：
1.3
作者：
Cui, Peng;Hou, Yuansheng;Lei, Fumin
通讯作者：
Lei, Fumin
影响因子：
5.4
作者：
Chen, HL;Li, YB;Kawaoka, Y
通讯作者：
Kawaoka, Y