Prevalence of the metabolic syndrome and its association with cardiovascular diseases in Korea.

Prevalence of the metabolic syndrome and its association with cardiovascular diseases in Korea.
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DOI:
10.3346/jkms.2004.19.2.195
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发表时间:
2004-04
影响因子:
4.5
通讯作者:
Shin YJ
Shin YJ
中科院分区:
医学4区
文献类型:
--
作者:
Kim MH;Kim MK;Choi BY;Shin YJ

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本研究旨在评估全国范围内代谢综合征的患病率,并确定其与心血管疾病的关系。分析了1998年韩国全国健康和营养调查的6,147名成年人的全国代表性样本的数据。根据ATP III的两种修正定义确定综合征,其中腹型肥胖以亚洲人腰围(WC)标准和腰臀比(WHR)确定。根据前者,男性患病率为22.1%,女性为27.8%。然而,基于后者,患病率分别为28.6%和27.8%。虽然在年轻组中,男性的年龄别流行率高于女性,但在老年组中,女性的年龄别流行率更高,因为其随年龄的上升幅度更大。在多元Logistic回归分析中,发现该综合征与心血管疾病呈正相关(男性WC和WHR的校正比值比(OR)分别为1.97和1.48,女性分别为1.54和1.31)。此外,其效应量超过了总胆固醇(男性校正OR为1.21,女性为1.08)或LDL胆固醇(男性为1.58,女性为1.22)。很明显,代谢综合征在韩国普遍存在,其对心血管疾病的重要性相当大。应立即实施预防策略,以避免心血管疾病在不久的将来流行。
This study aimed to estimate nationwide prevalence of the metabolic syndrome and to identify its association with cardiovascular diseases. The data on a national representative sample of 6,147 adults from 1998 Korea National Health and Nutrition Survey were analyzed. The syndrome was determined according to two kinds of modified definition from ATP III, in which abdominal obesity was determined by waist circumference (WC) standard for Asians and waist-to-hip ratio (WHR). Based on the former, prevalence was 22.1% in men and 27.8% in women. However, based on the latter, prevalence was 28.6% and 27.8%, respectively. Although age-specific prevalence was higher in men than in women among the younger group, it became higher in women among the older group because of its steeper rise with age. In multiple logistic regression, the syndrome was found to be positively associated with cardiovascular diseases (adjusted odds ratios (ORs)1.97 by WC and 1.48 by WHR in men, and 1.54 and 1.31 in women). Moreover, its effect size exceeded that of total cholesterol (adjusted ORs 1.21 in men, and 1.08 in women) or LDL cholesterol (1.58 in men and 1.22 in women). It is obvious that the metabolic syndrome prevails in Korea, and its importance regarding cardiovascular diseases is considerable. Prevention strategies should be implemented immediately to avoid cardiovascular epidemic in the near future.
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