Serologic evidence of H1 swine Influenza virus infection in swine farm residents and employees.
Serologic evidence of H1 swine Influenza virus infection in swine farm residents and employees.
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DOI：
10.3201/eid0808.010474
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发表时间：
2002-08
影响因子：
11.8
通讯作者：
Cox NJ
中科院分区：
文献类型：
--
作者：
Olsen CW;Brammer L;Easterday BC;Arden N;Belay E;Baker I;Cox NJ
我们评估了威斯康星州中南部农村的74名养猪场主人、员工、他们的家庭成员和兽医对猪和人H1流感病毒的血清阳性反应，并与114名威斯康星州密尔沃基的城市居民进行了比较。血清猪流感病毒血凝抑制抗体滴度为40的猪场参与者人数(17/74)显著高于城市对照样本阳性人数(1/0.001)。在农场参与者中，猪流感病毒的几何平均血清HI抗体效价也显著较高(p<；0.001)。猪病毒血清阳性与养殖场所有者或养殖场家庭成员、住在养殖场或每周4天进入猪舍有关(p<；0.05)。由于猪可以在产生新的基因流感病毒方面发挥作用，养猪户可能代表一个重要的哨兵群体来评估新的大流行流感病毒的出现。
We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemagglutination-inhibition (HI) antibody titers >40 to swine influenza viruses (17/74) was significantly higher (p<0.001) than the number of seropositive urban control samples (1/114). The geometric mean serum HI antibody titers to swine influenza viruses were also significantly higher (p<0.001) among the farm participants. Swine virus seropositivity was significantly (p<0.05) associated with being a farm owner or a farm family member, living on a farm, or entering the swine barn >4 days/week. Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses.
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DOI：
10.1073/pnas.031575198
发表时间：
2001-02-27
影响因子：
11.1
作者：
Basler, CF;Reid, AH;Taubenberger, JK
通讯作者：
Taubenberger, JK
影响因子：
3.8
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DOI：
10.1073/pnas.100140097
发表时间：
2000-06-06
影响因子：
11.1
作者：
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通讯作者：
Taubenberger, JK
影响因子：
168.9
作者：
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通讯作者：
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影响因子：
2.7
作者：
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通讯作者：
Karasin AI