Temporal lobe epilepsy in children.
Temporal lobe epilepsy in children.
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DOI:
10.1155/2012/849540
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发表时间:
2012
期刊:
影响因子:
--
通讯作者:
Wirrell EC
中科院分区:
文献类型:
--
作者:
Nickels KC;Wong-Kisiel LC;Moseley BD;Wirrell EC
The temporal lobe is a common focus for epilepsy. Temporal lobe epilepsy in infants and children differs from the relatively homogeneous syndrome seen in adults in several important clinical and pathological ways. Seizure semiology varies by age, and the ictal EEG pattern may be less clear cut than what is seen in adults. Additionally, the occurrence of intractable seizures in the developing brain may impact neurocognitive function remote from the temporal area. While many children will respond favorably to medical therapy, those with focal imaging abnormalities including cortical dysplasia, hippocampal sclerosis, or low-grade tumors are likely to be intractable. Expedient workup and surgical intervention in these medically intractable cases are needed to maximize long-term developmental outcome.
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