Novel amperometric glucose biosensor based on MXene nanocomposite.

Novel amperometric glucose biosensor based on MXene nanocomposite.
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DOI:
10.1038/srep36422
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发表时间:
2016-11-10
期刊:
影响因子:
4.6
通讯作者:
Alshareef HN
Alshareef HN
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Rakhi RB;Nayak P;Xia C;Alshareef HN

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A biosensor platform based on Au/MXene nanocomposite for sensitive enzymatic glucose detection is reported. The biosensor leverages the unique electrocatalytic properties and synergistic effects between Au nanoparticles and MXene sheets. An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). The biomediated Au nanoparticles play a significant role in facilitating the electron exchange between the electroactive center of GOx and the electrode. The GOx/Au/MXene/Nafion/GCE biosensor electrode displayed a linear amperometric response in the glucose concentration range from 0.1 to 18 mM with a relatively high sensitivity of 4.2 μAmM−1 cm−2 and a detection limit of 5.9 μM (S/N = 3). Furthermore, the biosensor exhibited excellent stability, reproducibility and repeatability. Therefore, the Au/MXene nanocomposite reported in this work is a potential candidate as an electrochemical transducer in electrochemical biosensors.
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