Ultrasonic Hydrogel Biochemical Sensor System

Ultrasonic Hydrogel Biochemical Sensor System
复制标题

超声波水凝胶生化传感器系统

DOI:
10.1109/embc44109.2020.9176216
复制
发表时间:
2020
期刊:
2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC
影响因子:
--
通讯作者:
Song, Seunghyun
Song, Seunghyun
中科院分区:
--
文献类型:
--
作者:
Byun, Eunjeong;Nam, Juhong;Shim, Hyunji;Kim, Esther;Kim, Albert;Song, Seunghyun

文献摘要

参考文献

相似文献

在这项工作中,我们提出了一个概念验证的基于水凝胶的传感器系统,能够通过测量后向散射超声无线生化传感。该系统由沉积在薄玻璃基底上的二氧化硅纳米颗粒嵌入的水凝胶组成,呈现用于反向散射的两个界面(组织/水凝胶和水凝胶/玻璃),这允许系统输出在介入生物组织的声学特性(例如衰减、反射)的变化下不变。我们表征了二氧化硅纳米颗粒(声学造影剂)负载对水凝胶的溶胀比及其超声背散射特性的影响。我们演示了一个无线pH值测量使用双重模式的询问,反射率和时间延迟。超声波水凝胶pH传感器被证明具有0.2 pH水平变化的传感分辨率,无线传感距离约为10 cm。
In this work, we present a proof-of-concept hydrogel-based sensor system capable of wireless biochemical sensing through measuring backscattered ultrasound. The system consists of silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, presenting two interfaces for backscattering (tissue/hydrogel and hydrogel/glass), which allows for system output to be invariant under the change in acoustic properties (e.g. attenuation, reflection) of the intervening biological tissue. We characterize the effect of silica nanoparticles (acoustic contrast agents) loading on the hydrogel's swelling ratio and its ultrasonic backscattering properties. We demonstrate a wireless pH measurement using dual modes of interrogations, reflection ratio and time delay. The ultrasonic hydrogel pH sensor is demonstrated with a sensing resolution of 0.2 pH level change with a wireless sensing distance around 10 cm.
DOI: 10.1016/j.jconrel.2009.12.012
发表时间: 2010-02-15
影响因子: 10.8
作者:
Siegel, Ronald A.;Gu, Yuandong;Lei, Ming;Baldi, Antonio;Nuxoll, Eric E.;Ziaie, Babak
通讯作者: Ziaie, Babak
生物组织中的超声波散射
DOI: --
发表时间: 1992
期刊:
影响因子: --
作者:
K. Shung;G. Thieme;F. Dunn
通讯作者: F. Dunn
DOI: 10.1021/la048719y
发表时间: 2004-10-12
期刊: LANGMUIR
影响因子: 3.9
作者:
Lei, M;Gu, YD;Ziaie, B
通讯作者: Ziaie, B
DOI: 10.1016/j.snb.2017.12.085
发表时间: 2018-04-15
影响因子: 8.4
作者:
Park, J. H.;Kim, A.;Ziaie, B.
通讯作者: Ziaie, B.
DOI: 10.1089/dia.2006.8.112
发表时间: 2006-02-01
影响因子: 5.4
作者:
Lei, Ming;Baldi, Antonio;Ziaie, Babak
通讯作者: Ziaie, Babak