Food Allergy from Infancy Through Adulthood.
Food Allergy from Infancy Through Adulthood.
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DOI：
10.1016/j.jaip.2020.02.010
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发表时间：
2020-06
期刊：
影响因子：
--
通讯作者：
Nadeau KC
中科院分区：
文献类型：
--
作者：
Sicherer SH;Warren CM;Dant C;Gupta RS;Nadeau KC
食物过敏是免疫反应导致对食物产生不良反应的结果。对食物的免疫反应可能会产生一系列症状和病症，包括急性过敏反应和过敏反应、食物蛋白诱发的过敏性直肠结肠炎、食物蛋白诱发的小肠结肠炎综合征、食物依赖性运动诱发的过敏反应和口腔过敏综合征（花粉食物过敏综合征）。食物过敏反应还会导致慢性炎症性疾病，例如嗜酸性粒细胞性食管炎和特应性皮炎。尽管食物过敏会影响从婴儿期到成年期的人，但不同年龄的过敏特征（即表现、触发因素和自然病程）不同，这对诊断、预后和治疗具有重要意义。新的食物过敏可以在任何年龄发生，我们提出无论是在婴儿期还是成年期，新发食物过敏的病因学都有相似之处。管理食物过敏的方法在生命过程中发生巨大变化，医生和患者必须做出相应的反应以优化护理。食物过敏疗法正在兴起，这些干预措施的有效性和安全性可能因治疗者的年龄组而异。在这篇综述中，我们重点介绍了对不同年龄段食物过敏的病因和特征的有趣观察，并讨论了与生命阶段相关的临床管理。
Food allergies are the result of immune responses that cause adverse reactions to foods. Immune responses to foods may produce a spectrum of symptoms and disorders, including acute allergic reactions and anaphylaxis, food protein-induced allergic proctocolitis, food protein-induced enterocolitis syndrome, food-dependent exercise-induced anaphylaxis, and oral allergy syndrome (pollen-food allergy syndrome). Food allergic responses also contribute to chronic inflammatory disorders such as eosinophilic esophagitis and atopic dermatitis. Although food allergy affects people from infancy through adulthood, there are allergic features that differ according to age (i.e., presentation, triggers, and natural course) that have important implications for diagnosis, prognosis, and management. New food allergies can develop at any age and we propose similarities in the etiology of de novo food allergy whether in infancy or adulthood. The approach to managing food allergy changes dramatically over the life course, and physicians and patients must respond accordingly to optimize care. Food allergy therapies are emerging and the efficacy and safety of these interventions could differ by age group of those treated. In this review, we highlight interesting observations on the etiology and characteristics of food allergy presenting at different ages, and discuss clinical management as it relates to life stage.
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影响因子：
7.7
作者：
Dellon ES;Kim HP;Sperry SL;Rybnicek DA;Woosley JT;Shaheen NJ
通讯作者：
Shaheen NJ
影响因子：
14.2
作者：
Davidson, Wendy F.;Leung, Donald Y. M.;Plaut, Marshall
通讯作者：
Plaut, Marshall
影响因子：
14.2
作者：
Crespo, JF;Rodríguez, J;Muzquiz, M
通讯作者：
Muzquiz, M
影响因子：
3.2
作者：
Annunziato, Rachel A.;Rubes, Melissa;Shemesh, Eyal
通讯作者：
Shemesh, Eyal
DOI：
10.2332/allergolint.c-08-62
发表时间：
2008-12-01
期刊：
Allergology international : official journal of the Japanese Society of Allergology
影响因子：
--
作者：
Bito, Toshinori;Kanda, Eriko;Nishigori, Chikako
通讯作者：
Nishigori, Chikako