The prevalence of antibodies to SARS-CoV-2 among blood donors in China.
The prevalence of antibodies to SARS-CoV-2 among blood donors in China.
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DOI：
10.1038/s41467-021-21503-x
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发表时间：
2021-03-02
影响因子：
16.6
通讯作者：
Wang L
中科院分区：
文献类型：
--
作者：
Chang L;Hou W;Zhao L;Zhang Y;Wang Y;Wu L;Xu T;Wang L;Wang J;Ma J;Wang L;Zhao J;Xu J;Dong J;Yan Y;Yang R;Li Y;Guo F;Cheng W;Su Y;Zeng J;Han W;Cheng T;Zhang J;Yuan Q;Xia N;Wang L
在这项研究中，我们调查了中国武汉、深圳和石家庄的献血者中SARS-CoV-2抗体的血清阳性率。2020年1 - 4月，对3市38144名健康献血者进行了SARS-CoV-2总抗体检测，随后进行了假型SARS-CoV-2中和试验、IgG和IgM抗体检测。最终，共有398名捐赠者被确认为阳性。年龄和性别标准化的18-60岁成人（深圳18-65岁）SARS-CoV-2血清阳性率在武汉为2.66% (95% CI: 2.24%-3.07%)，在深圳为0.033% (95% CI: 0.0029%-0.267%)，在石家庄为0.0028% （95% CI: 0.0001%-0.158%）。女性和年龄是武汉市献血者SARS-CoV-2血清阳性的独立危险因素。由于在COVID-19大流行的早期浪潮中，中国大多数人口未被感染，因此在疫苗广泛使用之前，仍然需要有效的公共卫生措施来阻止病毒传播。在这里，作者确定了2020年1月至4月期间中国武汉、深圳和石家庄的健康献血者中SARS-CoV-2抗体的血清阳性率。年龄和性别标准化的18-60岁成人SARS-CoV-2血清阳性率最高，为2.66%。
In this study, we investigate the seroprevalence of SARS-CoV-2 antibodies among blood donors in the cities of Wuhan, Shenzhen, and Shijiazhuang in China. From January to April 2020, 38,144 healthy blood donors in the three cities were tested for total antibody against SARS-CoV-2 followed by pseudotype SARS-CoV-2 neutralization tests, IgG, and IgM antibody testing. Finally, a total of 398 donors were confirmed positive. The age- and sex-standardized SARS-CoV-2 seroprevalence among 18–60 year-old adults (18–65 year-old in Shenzhen) was 2.66% (95% CI: 2.24%–3.07%) in Wuhan, 0.033% (95% CI: 0.0029%–0.267%) in Shenzhen, and 0.0028% (95% CI: 0.0001%–0.158%) in Shijiazhuang, respectively. Female sex and older-age were identified to be independent risk factors for SARS-CoV-2 seropositivity among blood donors in Wuhan. As most of the population of China remained uninfected during the early wave of the COVID-19 pandemic, effective public health measures are still certainly required to block viral spread before a vaccine is widely available. Here, the authors determine seroprevalence of antibodies to SARS-CoV-2 in healthy blood donors in the cities of Wuhan, Shenzhen, and Shijiazhuang in China between January and April 2020. The age- and sex-standardized SARS-CoV-2 seroprevalence among 18–60 year-old adults is, with 2.66%, the highest in Wuhan.
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DOI：
10.1016/j.cmi.2020.09.044
发表时间：
2021-03
期刊：
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
影响因子：
--
作者：
Pan Y;Li X;Yang G;Fan J;Tang Y;Hong X;Guo S;Li J;Yao D;Cheng Z;Yuan Y;Li Y;Wang X
通讯作者：
Wang X
DOI：
10.4049/jimmunol.1601896
发表时间：
2017-05-15
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Channappanavar R;Fett C;Mack M;Ten Eyck PP;Meyerholz DK;Perlman S
通讯作者：
Perlman S
影响因子：
82.9
作者：
Long, Quan-Xin;Liu, Bai-Zhong;Huang, Ai-Long
通讯作者：
Huang, Ai-Long
影响因子：
24.8
作者：
Isho B;Abe KT;Zuo M;Jamal AJ;Rathod B;Wang JH;Li Z;Chao G;Rojas OL;Bang YM;Pu A;Christie-Holmes N;Gervais C;Ceccarelli D;Samavarchi-Tehrani P;Guvenc F;Budylowski P;Li A;Paterson A;Yue FY;Marin LM;Caldwell L;Wrana JL;Colwill K;Sicheri F;Mubareka S;Gray-Owen SD;Drews SJ;Siqueira WL;Barrios-Rodiles M;Ostrowski M;Rini JM;Durocher Y;McGeer AJ;Gommerman JL;Gingras AC
通讯作者：
Gingras AC
影响因子：
13.8
作者：
Liu A;Li Y;Wan Z;Wang W;Lei X;Lv Y
通讯作者：
Lv Y